In the age of increasingly competent artificial intelligence (AI), understanding human–computer interactions is crucial. Five premises are proposed to guide this understanding. First, the primacy of structures: social, cultural, political, and historical structures shape both humans and AI systems. These structures influence how individuals and machines think, behave, and interact. Second, humans desire some level of autonomy and freedom, even if they are influenced by AI systems. This desire drives individuals to act in ways that assert their autonomy, even in the face of AI guidance. Third, whether human–computer interactions serve foundational values like truth, goodness, and beauty depends on human awakening and the application of traditional philosophical and scientific traditions. Fourth, values emerging from human–computer interactions may become mainstream, even if not consciously recognized. These values can influence societal norms and challenge existing values. Fifth, human–computer interactions are changing and will continue to change human-to-human and human-nature interactions. Balancing these three spheres is essential for human flourishing. The article emphasizes the need for interdisciplinary research to understand how AI systems affect human minds and society. It also highlights the importance of considering the ethical implications of AI development and the need for ongoing dialogue between technology and society. The article concludes by questioning what it means to be human in the age of AI. The authors argue that understanding these dynamics is essential for ensuring that AI systems contribute positively to human well-being. The article also notes the importance of respecting traditional values and cultures in shaping human–computer interactions. Finally, it calls for a dynamic, complex, and dialectical exploration of human–AI interactions to ensure that AI systems support human flourishing.In the age of increasingly competent artificial intelligence (AI), understanding human–computer interactions is crucial. Five premises are proposed to guide this understanding. First, the primacy of structures: social, cultural, political, and historical structures shape both humans and AI systems. These structures influence how individuals and machines think, behave, and interact. Second, humans desire some level of autonomy and freedom, even if they are influenced by AI systems. This desire drives individuals to act in ways that assert their autonomy, even in the face of AI guidance. Third, whether human–computer interactions serve foundational values like truth, goodness, and beauty depends on human awakening and the application of traditional philosophical and scientific traditions. Fourth, values emerging from human–computer interactions may become mainstream, even if not consciously recognized. These values can influence societal norms and challenge existing values. Fifth, human–computer interactions are changing and will continue to change human-to-human and human-nature interactions. Balancing these three spheres is essential for human flourishing. The article emphasizes the need for interdisciplinary research to understand how AI systems affect human minds and society. It also highlights the importance of considering the ethical implications of AI development and the need for ongoing dialogue between technology and society. The article concludes by questioning what it means to be human in the age of AI. The authors argue that understanding these dynamics is essential for ensuring that AI systems contribute positively to human well-being. The article also notes the importance of respecting traditional values and cultures in shaping human–computer interactions. Finally, it calls for a dynamic, complex, and dialectical exploration of human–AI interactions to ensure that AI systems support human flourishing.