This study assesses flood vulnerability in Mirzadhare, Charsadda district, Khyber Pakhtunkhwa, Pakistan, using an innovative framework that integrates the Analytical Hierarchy Process (AHP) and Geographic Information System (GIS). The study evaluates the vulnerability of settlements to floods based on four indicators: population density, average land GDP, distance to rivers, and land use and cover (LULC). The AHP technique is used to establish a hierarchical structure for the selected indicators, while GIS is employed to create vulnerability maps. The results reveal a high degree of vulnerability in the region, with over 60% of the area being arable land and highly susceptible to floods. The population and their land-use setup show high and extremely high values of vulnerability, respectively. The study provides thematic maps and detailed analysis, contributing to effective vulnerability management and flood risk reduction in the study area. Key recommendations include monitoring water levels, training local communities, controlling human encroachment, and implementing protective measures such as levees and dams.This study assesses flood vulnerability in Mirzadhare, Charsadda district, Khyber Pakhtunkhwa, Pakistan, using an innovative framework that integrates the Analytical Hierarchy Process (AHP) and Geographic Information System (GIS). The study evaluates the vulnerability of settlements to floods based on four indicators: population density, average land GDP, distance to rivers, and land use and cover (LULC). The AHP technique is used to establish a hierarchical structure for the selected indicators, while GIS is employed to create vulnerability maps. The results reveal a high degree of vulnerability in the region, with over 60% of the area being arable land and highly susceptible to floods. The population and their land-use setup show high and extremely high values of vulnerability, respectively. The study provides thematic maps and detailed analysis, contributing to effective vulnerability management and flood risk reduction in the study area. Key recommendations include monitoring water levels, training local communities, controlling human encroachment, and implementing protective measures such as levees and dams.