The report "Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective" by the World Cancer Research Fund and the American Institute for Cancer Research provides a comprehensive review of the evidence linking diet, nutrition, physical activity, and body composition to cancer prevention. The report is structured into three main parts: background, evidence and judgments, and recommendations. **Background:** - **International Variations and Trends:** Chapter 1 highlights the changes in food systems, diets, physical activity, and body composition throughout history, noting significant variations in cancer patterns across different regions. - **The Cancer Process:** Chapter 2 outlines the biology of cancer, emphasizing the role of environmental factors such as diet, nutrition, physical activity, and body composition in modifying cancer risk. - **Judging the Evidence:** Chapter 3 discusses the types of evidence considered, including epidemiological and experimental studies, and the methods used to assess and judge the evidence. **Evidence and Judgments:** - **Foods and Drinks:** Chapter 4 focuses on the types of food and drinks, with recommendations based on the most robust evidence. - **Physical Activity and Body Composition:** Chapters 5 and 6 address physical activity and body composition, highlighting the importance of an integrated approach to cancer prevention. - **Cancers:** Chapter 7 summarizes the evidence for 17 cancer sites, providing specific recommendations for each. - **Obesity:** Chapter 8 identifies how food, nutrition, and physical activity affect the risk of obesity and associated factors. - **Cancer Survivors:** Chapter 9 discusses the relevance of these factors for people living with cancer and the prevention of recurrent cancer. - **Research Issues:** Chapter 11 identifies areas for future research to refine understanding and improve cancer prevention. **Recommendations:** - **Public Health Goals and Personal Recommendations:** Chapter 12 presents the Panel's recommendations, which are based on 'convincing' or 'probable' evidence. The recommendations cover maintaining a healthy weight, being physically active, limiting consumption of energy-dense foods and sugary drinks, eating more plant-based foods, limiting red and processed meat, limiting alcohol, and avoiding dietary supplements. - **Special Recommendations:** The report includes specific recommendations for breastfeeding and cancer survivors, emphasizing the importance of these practices in cancer prevention. The report aims to guide public health policies and personal choices to reduce the incidence of cancer worldwide.The report "Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective" by the World Cancer Research Fund and the American Institute for Cancer Research provides a comprehensive review of the evidence linking diet, nutrition, physical activity, and body composition to cancer prevention. The report is structured into three main parts: background, evidence and judgments, and recommendations. **Background:** - **International Variations and Trends:** Chapter 1 highlights the changes in food systems, diets, physical activity, and body composition throughout history, noting significant variations in cancer patterns across different regions. - **The Cancer Process:** Chapter 2 outlines the biology of cancer, emphasizing the role of environmental factors such as diet, nutrition, physical activity, and body composition in modifying cancer risk. - **Judging the Evidence:** Chapter 3 discusses the types of evidence considered, including epidemiological and experimental studies, and the methods used to assess and judge the evidence. **Evidence and Judgments:** - **Foods and Drinks:** Chapter 4 focuses on the types of food and drinks, with recommendations based on the most robust evidence. - **Physical Activity and Body Composition:** Chapters 5 and 6 address physical activity and body composition, highlighting the importance of an integrated approach to cancer prevention. - **Cancers:** Chapter 7 summarizes the evidence for 17 cancer sites, providing specific recommendations for each. - **Obesity:** Chapter 8 identifies how food, nutrition, and physical activity affect the risk of obesity and associated factors. - **Cancer Survivors:** Chapter 9 discusses the relevance of these factors for people living with cancer and the prevention of recurrent cancer. - **Research Issues:** Chapter 11 identifies areas for future research to refine understanding and improve cancer prevention. **Recommendations:** - **Public Health Goals and Personal Recommendations:** Chapter 12 presents the Panel's recommendations, which are based on 'convincing' or 'probable' evidence. The recommendations cover maintaining a healthy weight, being physically active, limiting consumption of energy-dense foods and sugary drinks, eating more plant-based foods, limiting red and processed meat, limiting alcohol, and avoiding dietary supplements. - **Special Recommendations:** The report includes specific recommendations for breastfeeding and cancer survivors, emphasizing the importance of these practices in cancer prevention. The report aims to guide public health policies and personal choices to reduce the incidence of cancer worldwide.