This article explores the application of fractal design concepts in stretchable electronics, which are essential for integrating with soft materials and curvilinear surfaces. The authors demonstrate that thin films of hard electronic materials, patterned into deterministic fractal motifs and bonded to elastomers, enable unique mechanical properties that are beneficial for stretchable device design. Specifically, they show that fractal constructs such as Peano, Greek cross, and Vicsek patterns can be used to create space-filling structures of electronic materials, including monocrystalline silicon, for various applications such as electrophysiological sensors, precision monitors, actuators, and radio frequency antennas. These devices can conformally mount on the skin and exhibit properties like invisibility under magnetic resonance imaging (MRI). The study suggests that fractal-based layouts are important strategies for integrating hard and soft materials in stretchable electronics, offering new design opportunities and potential applications in biomedical systems.This article explores the application of fractal design concepts in stretchable electronics, which are essential for integrating with soft materials and curvilinear surfaces. The authors demonstrate that thin films of hard electronic materials, patterned into deterministic fractal motifs and bonded to elastomers, enable unique mechanical properties that are beneficial for stretchable device design. Specifically, they show that fractal constructs such as Peano, Greek cross, and Vicsek patterns can be used to create space-filling structures of electronic materials, including monocrystalline silicon, for various applications such as electrophysiological sensors, precision monitors, actuators, and radio frequency antennas. These devices can conformally mount on the skin and exhibit properties like invisibility under magnetic resonance imaging (MRI). The study suggests that fractal-based layouts are important strategies for integrating hard and soft materials in stretchable electronics, offering new design opportunities and potential applications in biomedical systems.