This study aimed to analyze family functionality and depression in older adults with diabetes. An observational, descriptive, and cross-sectional study was conducted at the Casa Blanca Family Medicine Clinic, ISSSTE, Tabasco, involving 195 older adults with diabetes between January and June 2023. The Yesavage Geriatric Depression Scale and the Apgar Family were used to assess depression and family functionality, respectively. Data were analyzed using descriptive statistics and Spearman correlation. **Results:** - The majority of participants were aged 60-70 years (53%), female (60.5%), married or in a union (71.3%), pensioners (42%), with basic education (48.7%), and unemployed (90.3%). - No data on depression were found in 81.5% of participants, mild depression in 14.9%, moderate in 2.1%, and severe in 1.5%. - 88.2% perceived a functional family, with moderate dysfunction (9.2%) and severe dysfunction (2.6%). - Higher family functionality was associated with a lower prevalence of depression in older adults. **Conclusions:** Family functionality is crucial for the adequate development of all its members, especially the elderly, who are more prone to depression. Early detection, diagnosis, and multidisciplinary treatment of depression, along with social and family support, are essential to improve the quality of life for older adults with diabetes. **Keywords:** Family functionality, depression, older adultsThis study aimed to analyze family functionality and depression in older adults with diabetes. An observational, descriptive, and cross-sectional study was conducted at the Casa Blanca Family Medicine Clinic, ISSSTE, Tabasco, involving 195 older adults with diabetes between January and June 2023. The Yesavage Geriatric Depression Scale and the Apgar Family were used to assess depression and family functionality, respectively. Data were analyzed using descriptive statistics and Spearman correlation. **Results:** - The majority of participants were aged 60-70 years (53%), female (60.5%), married or in a union (71.3%), pensioners (42%), with basic education (48.7%), and unemployed (90.3%). - No data on depression were found in 81.5% of participants, mild depression in 14.9%, moderate in 2.1%, and severe in 1.5%. - 88.2% perceived a functional family, with moderate dysfunction (9.2%) and severe dysfunction (2.6%). - Higher family functionality was associated with a lower prevalence of depression in older adults. **Conclusions:** Family functionality is crucial for the adequate development of all its members, especially the elderly, who are more prone to depression. Early detection, diagnosis, and multidisciplinary treatment of depression, along with social and family support, are essential to improve the quality of life for older adults with diabetes. **Keywords:** Family functionality, depression, older adults