This study investigates gender differences in psychological help-seeking attitudes among individuals with depression in Turkey. The research uses data from the Türkiye Health Survey (THS) conducted by the Turkish Statistical Institute in 2016, 2019, and 2022. Binary logistic regression analysis was employed to determine the factors associated with seeking psychological help. The study found that variables such as survey year, age, education level, employment status, general health status, disease status, depression status, day hospital service status, daily activity status, tobacco use status, and alcohol use status are associated with the status of receiving psychological help. Gender-specific analysis revealed variations in the significance and impact of these variables among individuals seeking psychological help. The study emphasizes the importance of addressing factors associated with psychological help-seeking behavior in both men and women to develop effective mental health interventions. The findings suggest that women are more likely to seek psychological help than men, but there are also gender-specific differences in the factors influencing help-seeking behavior. The study highlights the need for targeted interventions to improve mental health outcomes and reduce the stigma associated with seeking psychological help. The results indicate that individuals with higher education levels, better general health, and those who experience depression are more likely to seek psychological help. Additionally, individuals who use tobacco and alcohol are more likely to seek psychological help. The study also found that individuals who are working are less likely to seek psychological help compared to non-working individuals. The findings underscore the importance of addressing gender differences in psychological help-seeking behavior to improve mental health outcomes in Turkey.This study investigates gender differences in psychological help-seeking attitudes among individuals with depression in Turkey. The research uses data from the Türkiye Health Survey (THS) conducted by the Turkish Statistical Institute in 2016, 2019, and 2022. Binary logistic regression analysis was employed to determine the factors associated with seeking psychological help. The study found that variables such as survey year, age, education level, employment status, general health status, disease status, depression status, day hospital service status, daily activity status, tobacco use status, and alcohol use status are associated with the status of receiving psychological help. Gender-specific analysis revealed variations in the significance and impact of these variables among individuals seeking psychological help. The study emphasizes the importance of addressing factors associated with psychological help-seeking behavior in both men and women to develop effective mental health interventions. The findings suggest that women are more likely to seek psychological help than men, but there are also gender-specific differences in the factors influencing help-seeking behavior. The study highlights the need for targeted interventions to improve mental health outcomes and reduce the stigma associated with seeking psychological help. The results indicate that individuals with higher education levels, better general health, and those who experience depression are more likely to seek psychological help. Additionally, individuals who use tobacco and alcohol are more likely to seek psychological help. The study also found that individuals who are working are less likely to seek psychological help compared to non-working individuals. The findings underscore the importance of addressing gender differences in psychological help-seeking behavior to improve mental health outcomes in Turkey.