This study investigates gender differences in psychological help-seeking attitudes among individuals experiencing depression in Türkiye. Utilizing microdata from the Türkiye Health Survey conducted by the Turkish Statistical Institute in 2016, 2019, and 2022, binary logistic regression analysis was employed to determine the factors associated with seeking psychological help. The findings reveal that variables such as survey year, age, education level, employment status, general health status, disease status, depression status, day service status in the hospital, daily activity status, tobacco use status, and alcohol use status are associated with the status of receiving psychological help. Gender-specific analysis indicates variations in the significance and impact of these variables among individuals seeking psychological help. The study concludes that gender plays a crucial role in the inclination to seek psychological help, with women generally showing more moderate behaviors compared to men. The findings highlight the importance of addressing these factors in the development of preventive strategies for mental health protection, particularly for both women and men.This study investigates gender differences in psychological help-seeking attitudes among individuals experiencing depression in Türkiye. Utilizing microdata from the Türkiye Health Survey conducted by the Turkish Statistical Institute in 2016, 2019, and 2022, binary logistic regression analysis was employed to determine the factors associated with seeking psychological help. The findings reveal that variables such as survey year, age, education level, employment status, general health status, disease status, depression status, day service status in the hospital, daily activity status, tobacco use status, and alcohol use status are associated with the status of receiving psychological help. Gender-specific analysis indicates variations in the significance and impact of these variables among individuals seeking psychological help. The study concludes that gender plays a crucial role in the inclination to seek psychological help, with women generally showing more moderate behaviors compared to men. The findings highlight the importance of addressing these factors in the development of preventive strategies for mental health protection, particularly for both women and men.