The book review discusses *Genetics and Analysis of Quantitative Traits* by Michael Lynch and Bruce Walsh, published in 1998. The review highlights the shift in quantitative genetics from studying Mendelian traits in plants and animals to focusing on complex traits responsible for genetic diseases. This shift has led to the development of methods for mapping quantitative trait loci (QTLs) using dense maps of microsatellite markers and computational methods. The book is praised for its comprehensive coverage of the field, clear writing, and practical examples, making it suitable as a reference, self-learning resource, or textbook. The review outlines the four main sections of the book: "The Foundations of Quantitative Genetics," "Quantitative Trait Loci," "Estimation Procedures," and "Appendices." Each section covers fundamental concepts, methods for detecting QTLs, and advanced topics in estimation procedures. The review concludes by noting the book's value for both novice and experienced researchers and the anticipation for the second volume, *Evolution and Selection of Quantitative Traits*.The book review discusses *Genetics and Analysis of Quantitative Traits* by Michael Lynch and Bruce Walsh, published in 1998. The review highlights the shift in quantitative genetics from studying Mendelian traits in plants and animals to focusing on complex traits responsible for genetic diseases. This shift has led to the development of methods for mapping quantitative trait loci (QTLs) using dense maps of microsatellite markers and computational methods. The book is praised for its comprehensive coverage of the field, clear writing, and practical examples, making it suitable as a reference, self-learning resource, or textbook. The review outlines the four main sections of the book: "The Foundations of Quantitative Genetics," "Quantitative Trait Loci," "Estimation Procedures," and "Appendices." Each section covers fundamental concepts, methods for detecting QTLs, and advanced topics in estimation procedures. The review concludes by noting the book's value for both novice and experienced researchers and the anticipation for the second volume, *Evolution and Selection of Quantitative Traits*.