The paper "Giving Consent to the Ineffable" by Daniel Villiger explores the ethical implications of psychedelic-assisted therapy (PAT) in mental healthcare. It argues that patients can give informed consent to PAT despite the transformative nature of psychedelic experiences, which makes it difficult to assess the expected value of the treatment. The author discusses the concept of transformative experiences, drawing on L.A. Paul's work, and examines how these experiences affect rational choice and informed consent. While some argue that patients cannot rationally choose to undergo PAT due to the inability to fully simulate the experience, Villiger contends that patients can understand the potential benefits and align their values with the treatment. The paper highlights the importance of providing patients with information about the possible epistemic and personal transformations associated with PAT and the connection between its transformative nature and therapeutic effects. It concludes that patients can give informed consent by understanding the potential outcomes and aligning their values with the treatment's goals, even if they cannot fully anticipate the psychedelic experience.The paper "Giving Consent to the Ineffable" by Daniel Villiger explores the ethical implications of psychedelic-assisted therapy (PAT) in mental healthcare. It argues that patients can give informed consent to PAT despite the transformative nature of psychedelic experiences, which makes it difficult to assess the expected value of the treatment. The author discusses the concept of transformative experiences, drawing on L.A. Paul's work, and examines how these experiences affect rational choice and informed consent. While some argue that patients cannot rationally choose to undergo PAT due to the inability to fully simulate the experience, Villiger contends that patients can understand the potential benefits and align their values with the treatment. The paper highlights the importance of providing patients with information about the possible epistemic and personal transformations associated with PAT and the connection between its transformative nature and therapeutic effects. It concludes that patients can give informed consent by understanding the potential outcomes and aligning their values with the treatment's goals, even if they cannot fully anticipate the psychedelic experience.