Glucose tolerance and cardiovascular mortality - Comparison of fasting and 2-hour diagnostic criteria

Glucose tolerance and cardiovascular mortality - Comparison of fasting and 2-hour diagnostic criteria

2001 | Borch-Johnsen, K.; Neil, A.; Balkau, B.; Larsen, S.; Nissinen, A.; Pekkanen, J.; Tuomilehto, J.; Jousilahti, P.; Lindstrom, J.; Pyorala, M.; Pyorala, K.; Eschwege, E.; Gallus, G.; Garancini, M.P.; Bouter, L.M.; Dekker, J.M.; Heine, R.J.; Nijpels, G.; Stehouwer, C.D.A.; Feskens, E.J.M.
The study by Borch-Johnsen et al. (2001) compared the predictive value of fasting blood glucose (FBG) and 2-hour postprandial glucose (2h-BG) criteria for cardiovascular mortality. The analysis was based on data from 10 European cohort studies involving 15,388 men and 7,126 women, with a median follow-up of 8.8 years. The results showed that the inclusion of FBG did not significantly improve the prediction of 2h-BG alone, while adding 2h-BG to FBG criteria significantly enhanced the prediction of mortality from all causes and cardiovascular disease. The study found that subjects with impaired glucose tolerance but normal FBG levels had the highest number of excess deaths. The findings suggest that the 2h-BG criterion is a better predictor of mortality than the FBG criterion. The study highlights the importance of using the 2-hour glucose test for diabetes diagnosis and its prognostic value in predicting cardiovascular outcomes.The study by Borch-Johnsen et al. (2001) compared the predictive value of fasting blood glucose (FBG) and 2-hour postprandial glucose (2h-BG) criteria for cardiovascular mortality. The analysis was based on data from 10 European cohort studies involving 15,388 men and 7,126 women, with a median follow-up of 8.8 years. The results showed that the inclusion of FBG did not significantly improve the prediction of 2h-BG alone, while adding 2h-BG to FBG criteria significantly enhanced the prediction of mortality from all causes and cardiovascular disease. The study found that subjects with impaired glucose tolerance but normal FBG levels had the highest number of excess deaths. The findings suggest that the 2h-BG criterion is a better predictor of mortality than the FBG criterion. The study highlights the importance of using the 2-hour glucose test for diabetes diagnosis and its prognostic value in predicting cardiovascular outcomes.
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