The guidelines provide a comprehensive overview of the management of valvular heart disease (VHD), focusing on acquired VHD and excluding endocarditis and congenital valve disease. They are intended to assist healthcare professionals in making informed decisions about the diagnosis and treatment of VHD, considering the impact on patient outcomes and the risk-benefit ratio of various diagnostic and therapeutic options. The guidelines cover patient evaluation, including clinical assessment, echocardiography, non-invasive and invasive investigations, and comorbidity assessment. They also address endocarditis prophylaxis, rheumatic fever prophylaxis, risk stratification, and management of associated conditions such as coronary artery disease and arrhythmias. Specific sections are dedicated to the management of aortic regurgitation (AR), aortic stenosis (AS), mitral regurgitation (MR), mitral stenosis, tricuspid regurgitation, and tricuspid stenosis. The guidelines emphasize the importance of a collaborative approach between cardiologists and cardiac surgeons, particularly in high-risk patients. They also highlight the need for careful risk stratification and shared decision-making, involving the patient and their family. The guidelines are based on the latest evidence and recommendations from the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS), aiming to improve the quality of care for patients with VHD.The guidelines provide a comprehensive overview of the management of valvular heart disease (VHD), focusing on acquired VHD and excluding endocarditis and congenital valve disease. They are intended to assist healthcare professionals in making informed decisions about the diagnosis and treatment of VHD, considering the impact on patient outcomes and the risk-benefit ratio of various diagnostic and therapeutic options. The guidelines cover patient evaluation, including clinical assessment, echocardiography, non-invasive and invasive investigations, and comorbidity assessment. They also address endocarditis prophylaxis, rheumatic fever prophylaxis, risk stratification, and management of associated conditions such as coronary artery disease and arrhythmias. Specific sections are dedicated to the management of aortic regurgitation (AR), aortic stenosis (AS), mitral regurgitation (MR), mitral stenosis, tricuspid regurgitation, and tricuspid stenosis. The guidelines emphasize the importance of a collaborative approach between cardiologists and cardiac surgeons, particularly in high-risk patients. They also highlight the need for careful risk stratification and shared decision-making, involving the patient and their family. The guidelines are based on the latest evidence and recommendations from the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS), aiming to improve the quality of care for patients with VHD.