The "Handbook of Proteolytic Enzymes" is a comprehensive resource edited by Alan J. Barrett, covering both aspartic and metallo peptidases. Volume 1 focuses on these two classes of enzymes, providing detailed information on their structure, function, and applications. The book is divided into several sections, including: 1. **Aspartic Peptidases**: This section covers various aspartic peptidases, such as Memapsin 1, Memapsin 2, Plasmepsins, and others. It also includes viral retropepsins and fungal, plant, and animal retrotransposon elements. 2. **Metallopeptidases**: This section provides an introduction to metallopeptidases and their catalytic mechanisms. It then delves into specific families and subfamilies, such as Clan MA, which includes sub clans E and M, and other clans like MC, MD, ME, MF, and MH. Each subfamily is detailed with specific enzymes and their functions. 3. **Other Families and Unassigned Metallopeptidases**: This part lists additional families of metallopeptidases not yet assigned to specific clans, along with enzymes that have not been classified into any known family. The book is structured to provide a thorough understanding of the diversity and functionality of proteolytic enzymes, making it a valuable resource for researchers and students in biochemistry, molecular biology, and related fields.The "Handbook of Proteolytic Enzymes" is a comprehensive resource edited by Alan J. Barrett, covering both aspartic and metallo peptidases. Volume 1 focuses on these two classes of enzymes, providing detailed information on their structure, function, and applications. The book is divided into several sections, including: 1. **Aspartic Peptidases**: This section covers various aspartic peptidases, such as Memapsin 1, Memapsin 2, Plasmepsins, and others. It also includes viral retropepsins and fungal, plant, and animal retrotransposon elements. 2. **Metallopeptidases**: This section provides an introduction to metallopeptidases and their catalytic mechanisms. It then delves into specific families and subfamilies, such as Clan MA, which includes sub clans E and M, and other clans like MC, MD, ME, MF, and MH. Each subfamily is detailed with specific enzymes and their functions. 3. **Other Families and Unassigned Metallopeptidases**: This part lists additional families of metallopeptidases not yet assigned to specific clans, along with enzymes that have not been classified into any known family. The book is structured to provide a thorough understanding of the diversity and functionality of proteolytic enzymes, making it a valuable resource for researchers and students in biochemistry, molecular biology, and related fields.