Heart failure is a life-threatening condition affecting approximately 26 million people worldwide, with survival rates worse than those for bowel, breast, or prostate cancer. The disease places significant stress on patients, caregivers, and healthcare systems, and the demand for healthcare services is expected to increase dramatically over the next decade due to aging populations, detrimental lifestyle changes, and improved survival rates for those who develop heart failure as the final stage of another disease. Despite the burden imposed by heart failure, awareness of the disease is poor, leading to many premature deaths. Most types of heart failure are preventable, and a healthy lifestyle can reduce risk. Public awareness campaigns focusing on recognizing symptoms and seeking immediate medical attention have the potential to improve outcomes and save lives. To address the global burden of heart failure, policy initiatives are needed to prioritize prevention and ensure equitable care. These initiatives should include public awareness programs, healthcare professional education, and support for patients and caregivers. Research is essential to establish evidence-based performance measures and develop new and affordable therapies. International collaborative research is crucial to benefit tens of millions of people worldwide. The prevention of heart failure should be a global health priority, with a focus on high-risk groups such as the elderly, socioeconomically disadvantaged, and those with chronic conditions. Lifestyle interventions, such as a healthy diet, regular exercise, and avoiding smoking, are cost-effective and can significantly reduce the risk of heart failure. Compliance with clinical practice guidelines is associated with improved outcomes, but there is variation in adherence across countries. Policy initiatives should encourage equity of care through performance measures and incentives. In conclusion, coordinated public awareness programs and strategic and political initiatives are needed to improve heart failure prevention and care globally.Heart failure is a life-threatening condition affecting approximately 26 million people worldwide, with survival rates worse than those for bowel, breast, or prostate cancer. The disease places significant stress on patients, caregivers, and healthcare systems, and the demand for healthcare services is expected to increase dramatically over the next decade due to aging populations, detrimental lifestyle changes, and improved survival rates for those who develop heart failure as the final stage of another disease. Despite the burden imposed by heart failure, awareness of the disease is poor, leading to many premature deaths. Most types of heart failure are preventable, and a healthy lifestyle can reduce risk. Public awareness campaigns focusing on recognizing symptoms and seeking immediate medical attention have the potential to improve outcomes and save lives. To address the global burden of heart failure, policy initiatives are needed to prioritize prevention and ensure equitable care. These initiatives should include public awareness programs, healthcare professional education, and support for patients and caregivers. Research is essential to establish evidence-based performance measures and develop new and affordable therapies. International collaborative research is crucial to benefit tens of millions of people worldwide. The prevention of heart failure should be a global health priority, with a focus on high-risk groups such as the elderly, socioeconomically disadvantaged, and those with chronic conditions. Lifestyle interventions, such as a healthy diet, regular exercise, and avoiding smoking, are cost-effective and can significantly reduce the risk of heart failure. Compliance with clinical practice guidelines is associated with improved outcomes, but there is variation in adherence across countries. Policy initiatives should encourage equity of care through performance measures and incentives. In conclusion, coordinated public awareness programs and strategic and political initiatives are needed to improve heart failure prevention and care globally.