Host Range and Emerging and Reemerging Pathogens

Host Range and Emerging and Reemerging Pathogens

Vol. 11, No. 12, December 2005 | Mark E.J. Woolhouse* and Sonya Gowtage-Sequeria*
The article by Mark E.J. Woolhouse and Sonya Gowtage-Sequeria reviews the literature on human pathogens, identifying 1,407 recognized species, 58% of which are zoonotic. Among these, 177 are considered emerging or reemerging. Zoonotic pathogens are twice as likely to be in this category compared to non-zoonotic ones. The study examines the relationship between host range and pathogen emergence or reemergence, finding that emerging and reemerging pathogens are not strongly associated with particular types of non-human hosts but are more likely to have broad host ranges. The drivers of pathogen emergence and reemergence include changes in land use, agriculture, demographic shifts, and societal changes. However, only a small minority of zoonotic pathogens have caused major epidemics in humans. The article also discusses the transmissibility of pathogens once they enter the human population, noting that most zoonotic pathogens are not highly transmissible and do not cause major epidemics. The study concludes that emerging and reemerging pathogens share some common features, such as being disproportionately viruses and having broad host ranges, but their diversity makes surveillance and monitoring challenging.The article by Mark E.J. Woolhouse and Sonya Gowtage-Sequeria reviews the literature on human pathogens, identifying 1,407 recognized species, 58% of which are zoonotic. Among these, 177 are considered emerging or reemerging. Zoonotic pathogens are twice as likely to be in this category compared to non-zoonotic ones. The study examines the relationship between host range and pathogen emergence or reemergence, finding that emerging and reemerging pathogens are not strongly associated with particular types of non-human hosts but are more likely to have broad host ranges. The drivers of pathogen emergence and reemergence include changes in land use, agriculture, demographic shifts, and societal changes. However, only a small minority of zoonotic pathogens have caused major epidemics in humans. The article also discusses the transmissibility of pathogens once they enter the human population, noting that most zoonotic pathogens are not highly transmissible and do not cause major epidemics. The study concludes that emerging and reemerging pathogens share some common features, such as being disproportionately viruses and having broad host ranges, but their diversity makes surveillance and monitoring challenging.
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