2 January 2024 | Monika Abramiuik, Paulina Mertowska, Karolina Frankowska, Paulina Świechowska-Startek, Małgorzata Satora, Grzegorz Polak, Izabela Dymanowska-Dyjak and Ewelina Grywalska
This review explores how selected dietary ingredients may influence the development and progression of endometriosis. Endometriosis is a chronic, hormone-dependent disease characterized by the presence of endometrial tissue outside the uterus. Due to limited treatment options and unsatisfactory cure rates, there is a need to explore dietary interventions that may alleviate symptoms and modify the disease course. The review highlights the role of nutrients with anti-inflammatory and antioxidant properties, including vitamins and trace elements, in influencing endometriosis pathogenesis. While many discoveries have been made, further interdisciplinary research is needed to develop personalized therapies for endometriosis.
The review discusses the impact of various dietary components, including vitamins, macro and micronutrients, and estrogen derivatives, on endometriosis. It emphasizes the importance of dietary modifications in managing symptoms and improving quality of life. Nutrient deficiencies, such as magnesium, iron, B vitamins, zinc, selenium, and folic acid, are common in endometriosis patients and can exacerbate symptoms. A diet rich in essential nutrients, possibly supplemented with vitamins and minerals, can play a key role in endometriosis treatment. However, supplementation should be guided by healthcare professionals to avoid adverse effects.
Vitamins C and E have antioxidant properties that may help reduce oxidative stress and inflammation associated with endometriosis. Vitamin D modulates immune responses and may reduce endometriosis lesions. Vitamin A, particularly all-trans-retinoic acid, may inhibit endometrial cell proliferation and reduce inflammation. B vitamins, including B1, B2, B6, B9, and B12, may have protective effects against endometriosis. Macroelements like calcium, magnesium, sodium, potassium, chloride, phosphorus, and sulfur are essential for overall health and may influence endometriosis progression. Microelements such as zinc, copper, iron, selenium, manganese, nickel, and chromium play critical roles in hormonal balance, immune function, and inflammatory processes. Fatty acids, particularly omega-3-PUFAs, may reduce inflammation and adhesion formation in endometriosis. Carbohydrates and proteins also have a role in endometriosis, with certain dietary patterns showing potential benefits. Overall, a balanced diet tailored to individual needs is crucial in managing endometriosis.This review explores how selected dietary ingredients may influence the development and progression of endometriosis. Endometriosis is a chronic, hormone-dependent disease characterized by the presence of endometrial tissue outside the uterus. Due to limited treatment options and unsatisfactory cure rates, there is a need to explore dietary interventions that may alleviate symptoms and modify the disease course. The review highlights the role of nutrients with anti-inflammatory and antioxidant properties, including vitamins and trace elements, in influencing endometriosis pathogenesis. While many discoveries have been made, further interdisciplinary research is needed to develop personalized therapies for endometriosis.
The review discusses the impact of various dietary components, including vitamins, macro and micronutrients, and estrogen derivatives, on endometriosis. It emphasizes the importance of dietary modifications in managing symptoms and improving quality of life. Nutrient deficiencies, such as magnesium, iron, B vitamins, zinc, selenium, and folic acid, are common in endometriosis patients and can exacerbate symptoms. A diet rich in essential nutrients, possibly supplemented with vitamins and minerals, can play a key role in endometriosis treatment. However, supplementation should be guided by healthcare professionals to avoid adverse effects.
Vitamins C and E have antioxidant properties that may help reduce oxidative stress and inflammation associated with endometriosis. Vitamin D modulates immune responses and may reduce endometriosis lesions. Vitamin A, particularly all-trans-retinoic acid, may inhibit endometrial cell proliferation and reduce inflammation. B vitamins, including B1, B2, B6, B9, and B12, may have protective effects against endometriosis. Macroelements like calcium, magnesium, sodium, potassium, chloride, phosphorus, and sulfur are essential for overall health and may influence endometriosis progression. Microelements such as zinc, copper, iron, selenium, manganese, nickel, and chromium play critical roles in hormonal balance, immune function, and inflammatory processes. Fatty acids, particularly omega-3-PUFAs, may reduce inflammation and adhesion formation in endometriosis. Carbohydrates and proteins also have a role in endometriosis, with certain dietary patterns showing potential benefits. Overall, a balanced diet tailored to individual needs is crucial in managing endometriosis.