Hydrogel wound dressings are promising materials for accelerating healing in wounds on movable parts, such as elbows, knees, wrists, and necks, due to their mechanical flexibility, adhesion, and bioactivities. These hydrogels can adapt to frequent movements and promote healing through their ability to adhere to wounds and provide a supportive environment. Recent advancements in hydrogel-based dressings have focused on improving their mechanical properties, such as stretchability, self-healing, and adhesion, as well as their bioactivities, including antibacterial and antioxidant functions. Hydrogels with strong adhesive properties, such as DTM hydrogel, have been developed to adhere to skin and internal organs, effectively stopping bleeding and promoting cell proliferation. The adhesion strength of these hydrogels is enhanced through hydrogen bonding and electrostatic interactions. Additionally, hydrogels like iGx/PHMGy have been designed to adhere to various tissues, including the liver, lungs, and heart, and maintain good adhesion even after washing and twisting. In terms of mechanical properties, hydrogels with chemical and physical crosslinking methods have been developed to provide high strength, flexibility, and self-healing capabilities. For example, QCS/PF hydrogel exhibits reversible elongation and relaxation, while GT-ATx/QCS/CD hydrogel demonstrates excellent self-healing properties. Similarly, SMA/CNFs/PAM hydrogel has been designed to withstand high strain and maintain its structure under frequent movements. Hydrogels also exhibit antibacterial and antioxidant activities, which are crucial for preventing infections and promoting healing. These activities are achieved through the incorporation of cationic polymers, antibiotics, and nanomaterials such as silver nanoparticles and zinc ions. For instance, hydrogels containing silver nanoparticles have shown high antibacterial efficacy against bacteria like S. aureus and E. coli. Additionally, hydrogels with zinc ions have demonstrated antibacterial properties and can promote collagen deposition and vascular remodeling, accelerating wound healing. Overall, hydrogel-based wound dressings offer a promising solution for treating wounds on movable parts due to their mechanical flexibility, adhesion, and bioactivities. These materials are expected to play a significant role in the future of wound care, particularly in clinical applications where rapid healing and infection prevention are critical.Hydrogel wound dressings are promising materials for accelerating healing in wounds on movable parts, such as elbows, knees, wrists, and necks, due to their mechanical flexibility, adhesion, and bioactivities. These hydrogels can adapt to frequent movements and promote healing through their ability to adhere to wounds and provide a supportive environment. Recent advancements in hydrogel-based dressings have focused on improving their mechanical properties, such as stretchability, self-healing, and adhesion, as well as their bioactivities, including antibacterial and antioxidant functions. Hydrogels with strong adhesive properties, such as DTM hydrogel, have been developed to adhere to skin and internal organs, effectively stopping bleeding and promoting cell proliferation. The adhesion strength of these hydrogels is enhanced through hydrogen bonding and electrostatic interactions. Additionally, hydrogels like iGx/PHMGy have been designed to adhere to various tissues, including the liver, lungs, and heart, and maintain good adhesion even after washing and twisting. In terms of mechanical properties, hydrogels with chemical and physical crosslinking methods have been developed to provide high strength, flexibility, and self-healing capabilities. For example, QCS/PF hydrogel exhibits reversible elongation and relaxation, while GT-ATx/QCS/CD hydrogel demonstrates excellent self-healing properties. Similarly, SMA/CNFs/PAM hydrogel has been designed to withstand high strain and maintain its structure under frequent movements. Hydrogels also exhibit antibacterial and antioxidant activities, which are crucial for preventing infections and promoting healing. These activities are achieved through the incorporation of cationic polymers, antibiotics, and nanomaterials such as silver nanoparticles and zinc ions. For instance, hydrogels containing silver nanoparticles have shown high antibacterial efficacy against bacteria like S. aureus and E. coli. Additionally, hydrogels with zinc ions have demonstrated antibacterial properties and can promote collagen deposition and vascular remodeling, accelerating wound healing. Overall, hydrogel-based wound dressings offer a promising solution for treating wounds on movable parts due to their mechanical flexibility, adhesion, and bioactivities. These materials are expected to play a significant role in the future of wound care, particularly in clinical applications where rapid healing and infection prevention are critical.