5 January 2024 | Varshan Gounden and Moganavelli Singh
Hydrogels are promising materials for wound healing due to their ability to provide a moist environment, absorb wound exudates, and support tissue repair. This review discusses the current and future prospects of hydrogels in wound healing, highlighting their advantages over traditional dressings. Hydrogels can be natural or synthetic, with natural polymers like chitosan, gelatin, hyaluronic acid, and alginate offering biocompatibility and biodegradability, while synthetic polymers provide tunable properties. Hydrogels can be modified to incorporate growth factors, antibacterial agents, and other biomolecules, enhancing their effectiveness in wound healing. They are particularly useful in treating chronic wounds, which are often associated with infections, inflammation, and impaired healing. Hydrogels can also be used in burn therapy, providing cooling and protection. The review also explores advanced hydrogels, such as sprayable and "smart" hydrogels, which offer improved functionality and monitoring capabilities. Despite their benefits, challenges remain in terms of mechanical strength, manufacturing, and long-term stability. Overall, hydrogels represent a significant advancement in wound care, offering a versatile and effective solution for improving wound healing outcomes.Hydrogels are promising materials for wound healing due to their ability to provide a moist environment, absorb wound exudates, and support tissue repair. This review discusses the current and future prospects of hydrogels in wound healing, highlighting their advantages over traditional dressings. Hydrogels can be natural or synthetic, with natural polymers like chitosan, gelatin, hyaluronic acid, and alginate offering biocompatibility and biodegradability, while synthetic polymers provide tunable properties. Hydrogels can be modified to incorporate growth factors, antibacterial agents, and other biomolecules, enhancing their effectiveness in wound healing. They are particularly useful in treating chronic wounds, which are often associated with infections, inflammation, and impaired healing. Hydrogels can also be used in burn therapy, providing cooling and protection. The review also explores advanced hydrogels, such as sprayable and "smart" hydrogels, which offer improved functionality and monitoring capabilities. Despite their benefits, challenges remain in terms of mechanical strength, manufacturing, and long-term stability. Overall, hydrogels represent a significant advancement in wound care, offering a versatile and effective solution for improving wound healing outcomes.