A systematic review of hydrogen-rich water (HRW) evaluates its potential health benefits. HRW, which contains dissolved molecular hydrogen, has been studied for its antioxidant, anti-inflammatory, and anti-apoptotic properties. The review included 25 articles, focusing on HRW's effects on exercise capacity, physical endurance, liver function, cardiovascular disease, mental health, and oxidative stress. While preliminary clinical trials show promising results, further research with larger sample sizes and rigorous methodologies is needed to confirm these findings. HRW may help reduce oxidative stress, improve cardiovascular health, and support mental well-being. It has also shown potential in managing conditions like chronic kidney disease, metabolic syndrome, and cancer. However, the long-term effects and mechanisms of action remain unclear. The review highlights the need for more high-quality studies to fully understand HRW's therapeutic potential.A systematic review of hydrogen-rich water (HRW) evaluates its potential health benefits. HRW, which contains dissolved molecular hydrogen, has been studied for its antioxidant, anti-inflammatory, and anti-apoptotic properties. The review included 25 articles, focusing on HRW's effects on exercise capacity, physical endurance, liver function, cardiovascular disease, mental health, and oxidative stress. While preliminary clinical trials show promising results, further research with larger sample sizes and rigorous methodologies is needed to confirm these findings. HRW may help reduce oxidative stress, improve cardiovascular health, and support mental well-being. It has also shown potential in managing conditions like chronic kidney disease, metabolic syndrome, and cancer. However, the long-term effects and mechanisms of action remain unclear. The review highlights the need for more high-quality studies to fully understand HRW's therapeutic potential.