The article "Hyperactive Ras in developmental disorders and cancer" by Suzanne Schubbert, Kevin Shannon, and Gideon Bollag, published in Nature Reviews Cancer (2007), discusses the role of hyperactive Ras in various developmental disorders and cancer. The authors explore how mutations in genes such as NF1, GAP, and SOS1 can lead to abnormal Ras signaling, which is crucial for cell growth and division. They highlight the importance of understanding these mechanisms to develop targeted therapies for diseases associated with Ras hyperactivity.The article "Hyperactive Ras in developmental disorders and cancer" by Suzanne Schubbert, Kevin Shannon, and Gideon Bollag, published in Nature Reviews Cancer (2007), discusses the role of hyperactive Ras in various developmental disorders and cancer. The authors explore how mutations in genes such as NF1, GAP, and SOS1 can lead to abnormal Ras signaling, which is crucial for cell growth and division. They highlight the importance of understanding these mechanisms to develop targeted therapies for diseases associated with Ras hyperactivity.