A study published in *Nature* (2015) reveals that IL17-producing γδ T cells and neutrophils collaborate to promote breast cancer metastasis. The research shows that breast cancer tumors induce a systemic inflammatory cascade, which leads to the expansion and polarization of neutrophils. These neutrophils suppress CD8+ T cells, which normally limit metastasis. Neutralizing IL17 or G-CSF, or removing γδ T cells, reduces neutrophil accumulation and their suppressive effect on T cells, thereby decreasing metastasis. The study also demonstrates that the absence of γδ T cells or neutrophils significantly reduces pulmonary and lymph node metastases without affecting primary tumor growth. The findings suggest that targeting the γδ T cell-IL17-neutrophil axis could be a new strategy to inhibit breast cancer metastasis. In breast cancer patients, increased neutrophil abundance is associated with worse metastasis-specific survival. Neutrophils have both pro- and anti-metastatic roles, but in this study, they are shown to promote metastasis by suppressing CD8+ T cells. The study also identifies that IL17 is upstream of G-CSF in the inflammatory cascade, and that γδ T cells are a key source of IL17. The research highlights the importance of the γδ T cell-IL17-neutrophil axis in breast cancer metastasis and suggests that targeting this pathway could be a promising therapeutic approach.A study published in *Nature* (2015) reveals that IL17-producing γδ T cells and neutrophils collaborate to promote breast cancer metastasis. The research shows that breast cancer tumors induce a systemic inflammatory cascade, which leads to the expansion and polarization of neutrophils. These neutrophils suppress CD8+ T cells, which normally limit metastasis. Neutralizing IL17 or G-CSF, or removing γδ T cells, reduces neutrophil accumulation and their suppressive effect on T cells, thereby decreasing metastasis. The study also demonstrates that the absence of γδ T cells or neutrophils significantly reduces pulmonary and lymph node metastases without affecting primary tumor growth. The findings suggest that targeting the γδ T cell-IL17-neutrophil axis could be a new strategy to inhibit breast cancer metastasis. In breast cancer patients, increased neutrophil abundance is associated with worse metastasis-specific survival. Neutrophils have both pro- and anti-metastatic roles, but in this study, they are shown to promote metastasis by suppressing CD8+ T cells. The study also identifies that IL17 is upstream of G-CSF in the inflammatory cascade, and that γδ T cells are a key source of IL17. The research highlights the importance of the γδ T cell-IL17-neutrophil axis in breast cancer metastasis and suggests that targeting this pathway could be a promising therapeutic approach.