The IMPACT 2002+ life cycle impact assessment (LCIA) methodology introduces a combined midpoint/damage approach, linking various life cycle inventory (LCI) results to four damage categories: human health, ecosystem quality, climate change, and resources. This method uses 14 midpoint categories to link elementary flows and other interventions. New concepts and methods have been developed to improve the assessment of human toxicity and ecotoxicity, including the calculation of Human Damage Factors for carcinogens and non-carcinogens, and the consideration of agricultural and livestock production levels for food contamination. The method also accounts for the intermittent nature of rainfall and the differences between indoor and outdoor emissions. The midpoint scores are expressed in units of a reference substance and can be normalized at either the midpoint or damage level. IMPACT 2002+ provides characterization factors for nearly 1500 different LCI results, which are available online. The methodology aims to combine the strengths of classical impact assessment methods and damage-oriented approaches, offering a more comprehensive and accurate representation of environmental impacts.The IMPACT 2002+ life cycle impact assessment (LCIA) methodology introduces a combined midpoint/damage approach, linking various life cycle inventory (LCI) results to four damage categories: human health, ecosystem quality, climate change, and resources. This method uses 14 midpoint categories to link elementary flows and other interventions. New concepts and methods have been developed to improve the assessment of human toxicity and ecotoxicity, including the calculation of Human Damage Factors for carcinogens and non-carcinogens, and the consideration of agricultural and livestock production levels for food contamination. The method also accounts for the intermittent nature of rainfall and the differences between indoor and outdoor emissions. The midpoint scores are expressed in units of a reference substance and can be normalized at either the midpoint or damage level. IMPACT 2002+ provides characterization factors for nearly 1500 different LCI results, which are available online. The methodology aims to combine the strengths of classical impact assessment methods and damage-oriented approaches, offering a more comprehensive and accurate representation of environmental impacts.