The article discusses the comparison of two methods for measuring hemoglobin A1 (HbA1), specifically electrophoresis and high-performance liquid chromatography (HPLC). The authors argue that using standard deviations (SDs) to compare the results of these methods is inappropriate due to the different coefficients of variation in the control populations. They suggest that expressing results as multiples of the mean value (MoM) in non-diabetic individuals might be a more acceptable approach. However, they acknowledge that this method still leads to discrepancies when comparing HbA1 with HbA1c. The authors recommend more standardization in the measurement of glycated hemoglobin and suggest that the guidelines from the European IDDM Policy Group should be reconsidered. The authors also emphasize the need for multiple search strategies to identify relevant randomized controlled trials for systematic reviews. Finally, they correct a physics misconception about energy consumption in accelerating cars, clarifying that the energy used is the same regardless of the force applied, but the distance traveled is shorter.The article discusses the comparison of two methods for measuring hemoglobin A1 (HbA1), specifically electrophoresis and high-performance liquid chromatography (HPLC). The authors argue that using standard deviations (SDs) to compare the results of these methods is inappropriate due to the different coefficients of variation in the control populations. They suggest that expressing results as multiples of the mean value (MoM) in non-diabetic individuals might be a more acceptable approach. However, they acknowledge that this method still leads to discrepancies when comparing HbA1 with HbA1c. The authors recommend more standardization in the measurement of glycated hemoglobin and suggest that the guidelines from the European IDDM Policy Group should be reconsidered. The authors also emphasize the need for multiple search strategies to identify relevant randomized controlled trials for systematic reviews. Finally, they correct a physics misconception about energy consumption in accelerating cars, clarifying that the energy used is the same regardless of the force applied, but the distance traveled is shorter.