Impact of Aging on Cardiovascular Diseases: From Chronological Observation to Biological Insights: JACC Family Series

Impact of Aging on Cardiovascular Diseases: From Chronological Observation to Biological Insights: JACC Family Series

May 2024 | Dong Zhao, MD, PhD; Yibin Wang, PhD; Nathan D. Wong, PhD; Jian'an Wang, MD, PhD
The article discusses the impact of aging on cardiovascular diseases (CVD) and highlights the importance of understanding both chronological and biological aging processes. It emphasizes that while chronological age is a fixed factor, biological age can be influenced by genetic and environmental factors. The study reviews the increasing burden of CVD in aging populations and the challenges in addressing this issue. It also explores the relationship between biological aging and CVD, noting that biological aging may play a significant role in the development of age-related diseases. The article discusses the patterns of CVD mortality and prevalence in different age groups and highlights the need for interventions that target both biological aging and modifiable risk factors. It also compares the patterns of CVD mortality with those of cancer, noting that while CVD mortality increases exponentially with age, cancer mortality shows a different pattern. The study concludes that the impact of biological aging on CVD can be modified through interventions that address modifiable risk factors and socioeconomic development. The article also highlights the importance of further research into the biological mechanisms of aging and the potential for developing interventions that can mitigate the effects of aging on CVD.The article discusses the impact of aging on cardiovascular diseases (CVD) and highlights the importance of understanding both chronological and biological aging processes. It emphasizes that while chronological age is a fixed factor, biological age can be influenced by genetic and environmental factors. The study reviews the increasing burden of CVD in aging populations and the challenges in addressing this issue. It also explores the relationship between biological aging and CVD, noting that biological aging may play a significant role in the development of age-related diseases. The article discusses the patterns of CVD mortality and prevalence in different age groups and highlights the need for interventions that target both biological aging and modifiable risk factors. It also compares the patterns of CVD mortality with those of cancer, noting that while CVD mortality increases exponentially with age, cancer mortality shows a different pattern. The study concludes that the impact of biological aging on CVD can be modified through interventions that address modifiable risk factors and socioeconomic development. The article also highlights the importance of further research into the biological mechanisms of aging and the potential for developing interventions that can mitigate the effects of aging on CVD.
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