Acne vulgaris is a common chronic inflammatory skin condition affecting millions globally, significantly impacting patients' quality of life. The condition involves complex interactions of genetic, hormonal, and environmental factors, including diet. Recent research highlights the role of nutrition in acne pathogenesis, with dietary components such as dairy, chocolate, and saturated fats potentially exacerbating the condition. Dairy products, particularly milk, are linked to increased insulin and IGF-1 levels, which can stimulate sebaceous gland activity and contribute to acne. Chocolate consumption is associated with increased insulin excretion and inflammatory responses, potentially worsening acne. Saturated and trans fatty acids also play a role in promoting inflammation and sebum production. Other foods, including alcohol, salted products, gluten, and high-sugar items, may also contribute to acne development. While some studies suggest a correlation between diet and acne, the evidence remains inconclusive, with conflicting results on the specific impact of different dietary components. Further research is needed to clarify the exact role of diet in acne pathogenesis and to develop effective dietary interventions. This review summarizes the current scientific understanding of the relationship between diet and acne, emphasizing the need for more rigorous studies to guide clinical practice and improve patient outcomes.Acne vulgaris is a common chronic inflammatory skin condition affecting millions globally, significantly impacting patients' quality of life. The condition involves complex interactions of genetic, hormonal, and environmental factors, including diet. Recent research highlights the role of nutrition in acne pathogenesis, with dietary components such as dairy, chocolate, and saturated fats potentially exacerbating the condition. Dairy products, particularly milk, are linked to increased insulin and IGF-1 levels, which can stimulate sebaceous gland activity and contribute to acne. Chocolate consumption is associated with increased insulin excretion and inflammatory responses, potentially worsening acne. Saturated and trans fatty acids also play a role in promoting inflammation and sebum production. Other foods, including alcohol, salted products, gluten, and high-sugar items, may also contribute to acne development. While some studies suggest a correlation between diet and acne, the evidence remains inconclusive, with conflicting results on the specific impact of different dietary components. Further research is needed to clarify the exact role of diet in acne pathogenesis and to develop effective dietary interventions. This review summarizes the current scientific understanding of the relationship between diet and acne, emphasizing the need for more rigorous studies to guide clinical practice and improve patient outcomes.