This meta-analysis examines the impacts of climate change on agriculture and adaptation strategies in Ethiopia, focusing on various sectors, adaptation methods, and challenges. The study identified 23 peer-reviewed articles from ScienceDirect and Web of Science, following PRISMA guidelines, and analyzed them using Stata version 13. The results show that climate change negatively affects agriculture, the environment, and society through altered temperature and rainfall patterns. Effective adaptation strategies, such as soil and water conservation, agroforestry, integrated soil fertility management, small-scale irrigation, improved crop varieties, and mixed cropping, have been implemented to mitigate these impacts. However, challenges such as lack of financing, institutional support, insufficient stakeholder involvement, ecological and sociocultural factors, and limited access to weather information persist. The meta-regression analysis indicates that effective implementation of adaptation practices reduces the risk of climate change impacts. The study concludes that holistic and integrated approaches, including sustainable land and water management and social resilience-building, are necessary to enhance the resilience of Ethiopian communities and ecosystems in the face of climate change.This meta-analysis examines the impacts of climate change on agriculture and adaptation strategies in Ethiopia, focusing on various sectors, adaptation methods, and challenges. The study identified 23 peer-reviewed articles from ScienceDirect and Web of Science, following PRISMA guidelines, and analyzed them using Stata version 13. The results show that climate change negatively affects agriculture, the environment, and society through altered temperature and rainfall patterns. Effective adaptation strategies, such as soil and water conservation, agroforestry, integrated soil fertility management, small-scale irrigation, improved crop varieties, and mixed cropping, have been implemented to mitigate these impacts. However, challenges such as lack of financing, institutional support, insufficient stakeholder involvement, ecological and sociocultural factors, and limited access to weather information persist. The meta-regression analysis indicates that effective implementation of adaptation practices reduces the risk of climate change impacts. The study concludes that holistic and integrated approaches, including sustainable land and water management and social resilience-building, are necessary to enhance the resilience of Ethiopian communities and ecosystems in the face of climate change.