The paper reviews the complex relationship between sleep, stress, and resilience, highlighting the positive role of good sleep in mitigating chronic stress. The neuroendocrine stress response, involving the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system (ANS), is discussed, along with the bidirectional effects of stress on sleep and the impact of stress on the wake-sleep cycle. The authors emphasize that low resilience is associated with higher stress and sleep disorders, while good sleep can enhance resilience and reduce stress. Recent studies show that cognitive-behavioral therapy for insomnia (CBT-I) improves sleep quality, reduces general stress, and alleviates depressive symptoms. The paper concludes by suggesting that improving sleep hygiene could be a valuable tool for enhancing stress resilience and overall well-being.The paper reviews the complex relationship between sleep, stress, and resilience, highlighting the positive role of good sleep in mitigating chronic stress. The neuroendocrine stress response, involving the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system (ANS), is discussed, along with the bidirectional effects of stress on sleep and the impact of stress on the wake-sleep cycle. The authors emphasize that low resilience is associated with higher stress and sleep disorders, while good sleep can enhance resilience and reduce stress. Recent studies show that cognitive-behavioral therapy for insomnia (CBT-I) improves sleep quality, reduces general stress, and alleviates depressive symptoms. The paper concludes by suggesting that improving sleep hygiene could be a valuable tool for enhancing stress resilience and overall well-being.