Since January 2020, Elsevier has established a COVID-19 resource center on its public news and information website, Elsevier Connect, providing free English and Mandarin information on the novel coronavirus. The company has granted permission to make all its COVID-19-related research available in PubMed Central and other public repositories, allowing unrestricted reuse and analysis with acknowledgment of the original source. In a brief report published in *Cell Host & Microbe*, researchers from Chungbuk National University and other institutions demonstrated that ferrets are highly susceptible to SARS-CoV-2 infection and can effectively transmit the virus through direct or indirect contact, recapitulating human infection and transmission. Key findings include: - Infected ferrets exhibited elevated body temperatures and virus replication. - SARS-CoV-2 was detected in nasal washes, saliva, urine, and feces up to 8 days post-infection. - Direct contact with infected ferrets resulted in infection in naive ferrets within 2 days. - Indirect contact with infected ferrets also led to positive viral RNA detection, suggesting airborne transmission. - Viral antigens were detected in nasal turbinate, trachea, lungs, and intestine, with acute bronchiolitis observed in infected lungs. These results highlight the ferret model as a valuable tool for studying SARS-CoV-2 infection and transmission, which may facilitate the development of therapeutics and vaccines.Since January 2020, Elsevier has established a COVID-19 resource center on its public news and information website, Elsevier Connect, providing free English and Mandarin information on the novel coronavirus. The company has granted permission to make all its COVID-19-related research available in PubMed Central and other public repositories, allowing unrestricted reuse and analysis with acknowledgment of the original source. In a brief report published in *Cell Host & Microbe*, researchers from Chungbuk National University and other institutions demonstrated that ferrets are highly susceptible to SARS-CoV-2 infection and can effectively transmit the virus through direct or indirect contact, recapitulating human infection and transmission. Key findings include: - Infected ferrets exhibited elevated body temperatures and virus replication. - SARS-CoV-2 was detected in nasal washes, saliva, urine, and feces up to 8 days post-infection. - Direct contact with infected ferrets resulted in infection in naive ferrets within 2 days. - Indirect contact with infected ferrets also led to positive viral RNA detection, suggesting airborne transmission. - Viral antigens were detected in nasal turbinate, trachea, lungs, and intestine, with acute bronchiolitis observed in infected lungs. These results highlight the ferret model as a valuable tool for studying SARS-CoV-2 infection and transmission, which may facilitate the development of therapeutics and vaccines.