The article reviews the inflammatory responses within various organs, focusing on the etiology of inflammation, inflammatory response mechanisms, resolution of inflammation, and organ-specific inflammatory responses. Inflammation is a biological response triggered by various factors, including pathogens, damaged cells, and toxic compounds, leading to acute or chronic responses in organs such as the heart, pancreas, liver, kidney, lung, brain, intestinal tract, and reproductive system. The inflammatory response involves the activation of signaling pathways like NF-κB, MAPK, and JAK-STAT, which regulate inflammatory mediator levels and recruit inflammatory cells. The article also discusses the role of inflammatory markers, cytokines, and proteins in inflammation and their implications for disease diagnosis and treatment. Additionally, it explores the resolution of inflammation and the impact of dysregulation on chronic inflammation and disease progression. The review highlights the importance of understanding these mechanisms to develop targeted therapies for inflammatory diseases.The article reviews the inflammatory responses within various organs, focusing on the etiology of inflammation, inflammatory response mechanisms, resolution of inflammation, and organ-specific inflammatory responses. Inflammation is a biological response triggered by various factors, including pathogens, damaged cells, and toxic compounds, leading to acute or chronic responses in organs such as the heart, pancreas, liver, kidney, lung, brain, intestinal tract, and reproductive system. The inflammatory response involves the activation of signaling pathways like NF-κB, MAPK, and JAK-STAT, which regulate inflammatory mediator levels and recruit inflammatory cells. The article also discusses the role of inflammatory markers, cytokines, and proteins in inflammation and their implications for disease diagnosis and treatment. Additionally, it explores the resolution of inflammation and the impact of dysregulation on chronic inflammation and disease progression. The review highlights the importance of understanding these mechanisms to develop targeted therapies for inflammatory diseases.