The Integrative Genomics Viewer (IGV) is a high-performance, user-friendly tool designed for visualizing and exploring large, diverse genomic datasets. It supports both array-based and next-generation sequencing (NGS) data, as well as clinical and phenotypic information. IGV's key features include its ability to handle large datasets efficiently, real-time interaction at various genome resolution scales, and flexible loading of local and remote data. The software is written in Java and runs on major platforms, offering a wide range of functionalities such as data tiling for efficient memory management, support for multiple file formats, and advanced visualization options for NGS data, variant calls, copy number and expression data, and genomic annotations. IGV also provides tools for saving and sharing sessions, and can be controlled via scripting, socket port, and HTTP interfaces. The tool is freely available under a GNU LGPL open-source license and is widely used in both academic and clinical research.The Integrative Genomics Viewer (IGV) is a high-performance, user-friendly tool designed for visualizing and exploring large, diverse genomic datasets. It supports both array-based and next-generation sequencing (NGS) data, as well as clinical and phenotypic information. IGV's key features include its ability to handle large datasets efficiently, real-time interaction at various genome resolution scales, and flexible loading of local and remote data. The software is written in Java and runs on major platforms, offering a wide range of functionalities such as data tiling for efficient memory management, support for multiple file formats, and advanced visualization options for NGS data, variant calls, copy number and expression data, and genomic annotations. IGV also provides tools for saving and sharing sessions, and can be controlled via scripting, socket port, and HTTP interfaces. The tool is freely available under a GNU LGPL open-source license and is widely used in both academic and clinical research.