The article discusses the application of the neural exposome concept to interdisciplinary fetal-neonatal neurology (FNN) training. The neural exposome refers to the dynamic interaction of genetic and environmental factors that influence brain development and health across the lifespan. FNN training, which spans the first 1,000 days of life, integrates reproductive, pregnancy, and pediatric healthcare to strengthen neonatal neurocritical care, pediatric, and adult neurology training. This training emphasizes the importance of shared clinical decisions, minimizing bias, and reducing cognitive errors. It also highlights the role of the neural exposome in understanding gene-environment interactions, particularly in the context of reproductive health and the maternal-placental-fetal triad. The article discusses the impact of toxic stressor interplay (TSI) on the neural exposome, which can lead to developmental disorders and epilepsy, particularly during the first 1,000 days. It also emphasizes the need for integrated approaches to address health disparities and improve neurologic outcomes across the lifespan. The article concludes with a call for interdisciplinary collaboration and the application of the neural exposome concept to improve neurologic care and health outcomes.The article discusses the application of the neural exposome concept to interdisciplinary fetal-neonatal neurology (FNN) training. The neural exposome refers to the dynamic interaction of genetic and environmental factors that influence brain development and health across the lifespan. FNN training, which spans the first 1,000 days of life, integrates reproductive, pregnancy, and pediatric healthcare to strengthen neonatal neurocritical care, pediatric, and adult neurology training. This training emphasizes the importance of shared clinical decisions, minimizing bias, and reducing cognitive errors. It also highlights the role of the neural exposome in understanding gene-environment interactions, particularly in the context of reproductive health and the maternal-placental-fetal triad. The article discusses the impact of toxic stressor interplay (TSI) on the neural exposome, which can lead to developmental disorders and epilepsy, particularly during the first 1,000 days. It also emphasizes the need for integrated approaches to address health disparities and improve neurologic outcomes across the lifespan. The article concludes with a call for interdisciplinary collaboration and the application of the neural exposome concept to improve neurologic care and health outcomes.