This technical report by Y Kanda investigates the freely available statistical software 'EZR' (Easy R), which is based on R and R Commander. EZR is designed to facilitate clinical studies by providing point-and-click access to commonly used statistical functions, such as survival analyses, competing risk analyses, receiver operating characteristic analyses, meta-analyses, and sample size calculations. The software is available for both Windows and Mac OS X and can be installed using a single installer. EZR includes a main operating window, 'EZR on R Commander,' where users can select various statistical functions from a menu bar. The report provides detailed instructions on how to create, modify, and save data sets, perform descriptive statistics, conduct statistical analyses for categorical and continuous variables, perform survival analysis, and perform competing risk analysis. EZR also supports diagnostic test accuracy analysis, matched-pair analysis, meta-analysis, and sample size calculation. The report concludes by highlighting the benefits of EZR for researchers conducting clinical studies, particularly in the field of hematopoietic SCT.This technical report by Y Kanda investigates the freely available statistical software 'EZR' (Easy R), which is based on R and R Commander. EZR is designed to facilitate clinical studies by providing point-and-click access to commonly used statistical functions, such as survival analyses, competing risk analyses, receiver operating characteristic analyses, meta-analyses, and sample size calculations. The software is available for both Windows and Mac OS X and can be installed using a single installer. EZR includes a main operating window, 'EZR on R Commander,' where users can select various statistical functions from a menu bar. The report provides detailed instructions on how to create, modify, and save data sets, perform descriptive statistics, conduct statistical analyses for categorical and continuous variables, perform survival analysis, and perform competing risk analysis. EZR also supports diagnostic test accuracy analysis, matched-pair analysis, meta-analysis, and sample size calculation. The report concludes by highlighting the benefits of EZR for researchers conducting clinical studies, particularly in the field of hematopoietic SCT.