The article discusses the high prevalence of Kaposi’s sarcoma (KS) among individuals with AIDS, suggesting it may be caused by an unidentified sexually transmitted infection. KS is at least 20,000 times more common in AIDS patients than in the general population and 300 times more common than in other immunosuppressed groups. Among AIDS patients, KS prevalence varied by HIV transmission group, with the highest rates in homosexual or bisexual men (21%) and the lowest in men with haemophilia (1%). Women with HIV acquired through heterosexual contact had higher KS risk if their partners were bisexual men. The risk was not consistently related to age or race but varied across the United States, with the highest rates in areas where the AIDS epidemic began. The study analyzed data from AIDS patients reported to the CDC, finding that the overall risk of KS in AIDS patients was significantly higher than in the general population. The risk was greatest in homosexual and bisexual men, and among women, those with bisexual partners had four times the risk of those with other partners. The study also found that KS was less common in children under 15 years old, suggesting a possible non-oral transmission route. The data support the hypothesis that KS in AIDS patients may be caused by an unidentified sexually transmitted infection, with transmission mainly through sexual contact. The study also found that the percentage of AIDS patients with KS declined over time, which may be due to changes in the CDC definition of AIDS or a shorter incubation period for KS. The findings suggest that KS is a common manifestation of AIDS and may be caused by an infectious agent, though the exact cause remains unknown. The article also discusses the geographical distribution of KS in the US, with higher rates in certain states and among individuals born in certain countries. The study concludes that KS in AIDS patients is likely caused by an unidentified sexually transmitted infection, and further research is needed to identify the specific agent.The article discusses the high prevalence of Kaposi’s sarcoma (KS) among individuals with AIDS, suggesting it may be caused by an unidentified sexually transmitted infection. KS is at least 20,000 times more common in AIDS patients than in the general population and 300 times more common than in other immunosuppressed groups. Among AIDS patients, KS prevalence varied by HIV transmission group, with the highest rates in homosexual or bisexual men (21%) and the lowest in men with haemophilia (1%). Women with HIV acquired through heterosexual contact had higher KS risk if their partners were bisexual men. The risk was not consistently related to age or race but varied across the United States, with the highest rates in areas where the AIDS epidemic began. The study analyzed data from AIDS patients reported to the CDC, finding that the overall risk of KS in AIDS patients was significantly higher than in the general population. The risk was greatest in homosexual and bisexual men, and among women, those with bisexual partners had four times the risk of those with other partners. The study also found that KS was less common in children under 15 years old, suggesting a possible non-oral transmission route. The data support the hypothesis that KS in AIDS patients may be caused by an unidentified sexually transmitted infection, with transmission mainly through sexual contact. The study also found that the percentage of AIDS patients with KS declined over time, which may be due to changes in the CDC definition of AIDS or a shorter incubation period for KS. The findings suggest that KS is a common manifestation of AIDS and may be caused by an infectious agent, though the exact cause remains unknown. The article also discusses the geographical distribution of KS in the US, with higher rates in certain states and among individuals born in certain countries. The study concludes that KS in AIDS patients is likely caused by an unidentified sexually transmitted infection, and further research is needed to identify the specific agent.