2020 | Yichun Cheng, Ran Luo, Kun Wang, Meng Zhang, Zhixiang Wang, Lei Dong, Junhua Li, Ying Yao, Shuwang Ge and Gang Xu
The COVID-19 Resource Centre, established by Elsevier in January 2020, provides free information in English and Mandarin on the novel coronavirus. The centre is hosted on Elsevier Connect and grants permission for all COVID-19-related research to be immediately available in PubMed Central and other public repositories, with unrestricted reuse and analysis rights, provided that the original source is acknowledged.
A study published in *Kidney International* by Yichun Cheng et al. found that kidney disease is associated with in-hospital death in patients with COVID-19. The study, conducted at a tertiary teaching hospital in Wuhan, China, included 701 patients with COVID-19, of whom 113 (16.1%) died in hospital. The prevalence of acute kidney injury (AKI) was 5.1%, and patients with kidney disease had a significantly higher risk of in-hospital death. Elevated baseline serum creatinine, elevated blood urea nitrogen, AKI stages, proteinuria, and hematuria were independent risk factors for in-hospital death after adjusting for age, sex, disease severity, comorbidities, and leukocyte count. The findings highlight the importance of early identification and intervention for kidney involvement in COVID-19 to improve patient prognosis.The COVID-19 Resource Centre, established by Elsevier in January 2020, provides free information in English and Mandarin on the novel coronavirus. The centre is hosted on Elsevier Connect and grants permission for all COVID-19-related research to be immediately available in PubMed Central and other public repositories, with unrestricted reuse and analysis rights, provided that the original source is acknowledged.
A study published in *Kidney International* by Yichun Cheng et al. found that kidney disease is associated with in-hospital death in patients with COVID-19. The study, conducted at a tertiary teaching hospital in Wuhan, China, included 701 patients with COVID-19, of whom 113 (16.1%) died in hospital. The prevalence of acute kidney injury (AKI) was 5.1%, and patients with kidney disease had a significantly higher risk of in-hospital death. Elevated baseline serum creatinine, elevated blood urea nitrogen, AKI stages, proteinuria, and hematuria were independent risk factors for in-hospital death after adjusting for age, sex, disease severity, comorbidities, and leukocyte count. The findings highlight the importance of early identification and intervention for kidney involvement in COVID-19 to improve patient prognosis.