Supplementary Figure III presents the results of an analysis examining the interaction network surrounding the VHL protein, up to two edges away. The analysis was conducted using both literature-derived interactions and interactions identified through IP-HTMS (Immunoprecipitation followed by High Throughput Mass Spectrometry). The results were validated using the Interaction Graph Validator.Supplementary Figure III presents the results of an analysis examining the interaction network surrounding the VHL protein, up to two edges away. The analysis was conducted using both literature-derived interactions and interactions identified through IP-HTMS (Immunoprecipitation followed by High Throughput Mass Spectrometry). The results were validated using the Interaction Graph Validator.