The paper presents a light-controlled soft bio-microrobot (referred to as "Ebot") based on *Euglena gracilis* that can perform multiple biomedical tasks in narrow microenvironments, including intestinal mucosa. The motion of the Ebot is precisely controlled by light-controlled polygonal flagellum beating, allowing for high controllability, deformability, and adaptability. The Ebot can deform and change its shape to pass through narrow and curved microchannels, making it suitable for tasks such as targeted drug delivery, selective removal of diseased cells, and photodynamic therapy (PDT). The Ebot's motion and deformation are influenced by light intensity and illumination duration, enabling precise navigation and task execution. The biocompatibility and biodegradability of the Ebot make it a promising tool for biomedical applications in confined spaces. The study demonstrates the Ebot's ability to navigate through microfluidic channels, deliver drugs to specific cells, remove diseased cells, and perform PDT, highlighting its potential for various biomedical tasks.The paper presents a light-controlled soft bio-microrobot (referred to as "Ebot") based on *Euglena gracilis* that can perform multiple biomedical tasks in narrow microenvironments, including intestinal mucosa. The motion of the Ebot is precisely controlled by light-controlled polygonal flagellum beating, allowing for high controllability, deformability, and adaptability. The Ebot can deform and change its shape to pass through narrow and curved microchannels, making it suitable for tasks such as targeted drug delivery, selective removal of diseased cells, and photodynamic therapy (PDT). The Ebot's motion and deformation are influenced by light intensity and illumination duration, enabling precise navigation and task execution. The biocompatibility and biodegradability of the Ebot make it a promising tool for biomedical applications in confined spaces. The study demonstrates the Ebot's ability to navigate through microfluidic channels, deliver drugs to specific cells, remove diseased cells, and perform PDT, highlighting its potential for various biomedical tasks.