1982-06-01 | Burgdorfer, W Barbour, AG Hayes, SF et al.
The article, published in *Science* in 1982, reports the discovery of a treponema-like spirochete in *Ixodes dammini*, the tick vector of Lyme disease. The spirochete was isolated from infected ticks and found to be associated with long-lasting cutaneous lesions in New Zealand White rabbits. Serum samples from Lyme disease patients were shown to contain antibodies to this agent, suggesting a causal relationship. The study also highlights the potential diagnostic value of indirect immunofluorescence for Lyme disease and emphasizes the need for further research into the epidemiology, ecology, and vector relationships of the spirochete and its tick vector.The article, published in *Science* in 1982, reports the discovery of a treponema-like spirochete in *Ixodes dammini*, the tick vector of Lyme disease. The spirochete was isolated from infected ticks and found to be associated with long-lasting cutaneous lesions in New Zealand White rabbits. Serum samples from Lyme disease patients were shown to contain antibodies to this agent, suggesting a causal relationship. The study also highlights the potential diagnostic value of indirect immunofluorescence for Lyme disease and emphasizes the need for further research into the epidemiology, ecology, and vector relationships of the spirochete and its tick vector.