MIMIC-III, a large, single-center database, compiles comprehensive clinical data from patients admitted to critical care units at Beth Israel Deaconess Medical Center in Boston, Massachusetts. The database includes vital signs, medications, laboratory measurements, observations, notes, fluid balance, procedure codes, diagnostic codes, imaging reports, hospital length of stay, and survival data. It supports various applications, including academic and industrial research, quality improvement initiatives, and higher education coursework. MIMIC-III is freely accessible under a data use agreement, enabling reproducibility and improvement of clinical studies worldwide. The database spans over a decade, with detailed information on individual patient care, and is the only freely accessible critical care database of its kind. The data is deidentified in accordance with HIPAA standards, ensuring patient privacy. The MIMIC-III database consists of 26 tables, linked by identifiers, and is designed to closely represent raw hospital data. Researchers must complete a recognized course and sign a data use agreement to access the database. MIMIC-III has been used in numerous educational institutions and research studies, and efforts are ongoing to map concepts to standardized dictionaries and transform the database into common data models.MIMIC-III, a large, single-center database, compiles comprehensive clinical data from patients admitted to critical care units at Beth Israel Deaconess Medical Center in Boston, Massachusetts. The database includes vital signs, medications, laboratory measurements, observations, notes, fluid balance, procedure codes, diagnostic codes, imaging reports, hospital length of stay, and survival data. It supports various applications, including academic and industrial research, quality improvement initiatives, and higher education coursework. MIMIC-III is freely accessible under a data use agreement, enabling reproducibility and improvement of clinical studies worldwide. The database spans over a decade, with detailed information on individual patient care, and is the only freely accessible critical care database of its kind. The data is deidentified in accordance with HIPAA standards, ensuring patient privacy. The MIMIC-III database consists of 26 tables, linked by identifiers, and is designed to closely represent raw hospital data. Researchers must complete a recognized course and sign a data use agreement to access the database. MIMIC-III has been used in numerous educational institutions and research studies, and efforts are ongoing to map concepts to standardized dictionaries and transform the database into common data models.