MXene is a promising nanomaterial with excellent antibacterial properties. It has been extensively studied for its potential in biomedical applications, including antimicrobial therapy. MXene is derived from MAX phases through chemical etching and mechanical processing, resulting in a two-dimensional material with a unique structure and properties. It exhibits high photothermal conversion efficiency, excellent hydrophilicity, and strong mechanical properties, making it suitable for various biomedical applications. MXene has shown significant potential in combating bacterial infections, particularly in the context of antibiotic resistance and biofilm formation. Its antimicrobial mechanisms include physical damage to bacterial membranes, induction of oxidative stress, and photothermal and photodynamic therapy. MXene-based composites have been explored for their antimicrobial applications, demonstrating promising results in inhibiting bacterial growth and promoting wound healing. The biocompatibility and biodegradability of MXene have also been investigated, with studies indicating that it is safe for biomedical use. However, further research is needed to fully understand its antimicrobial mechanisms and optimize its applications in the field of antibacterial therapy. Overall, MXene holds great promise as a versatile nanomaterial for antimicrobial applications.MXene is a promising nanomaterial with excellent antibacterial properties. It has been extensively studied for its potential in biomedical applications, including antimicrobial therapy. MXene is derived from MAX phases through chemical etching and mechanical processing, resulting in a two-dimensional material with a unique structure and properties. It exhibits high photothermal conversion efficiency, excellent hydrophilicity, and strong mechanical properties, making it suitable for various biomedical applications. MXene has shown significant potential in combating bacterial infections, particularly in the context of antibiotic resistance and biofilm formation. Its antimicrobial mechanisms include physical damage to bacterial membranes, induction of oxidative stress, and photothermal and photodynamic therapy. MXene-based composites have been explored for their antimicrobial applications, demonstrating promising results in inhibiting bacterial growth and promoting wound healing. The biocompatibility and biodegradability of MXene have also been investigated, with studies indicating that it is safe for biomedical use. However, further research is needed to fully understand its antimicrobial mechanisms and optimize its applications in the field of antibacterial therapy. Overall, MXene holds great promise as a versatile nanomaterial for antimicrobial applications.