The article discusses the development and potential of nanopesticides with minimizing carriers (NMC) as a sustainable and environmentally friendly alternative to traditional nanopesticides. NMCs are prepared through prodrug molecular design and molecular self-assembly, aiming to reduce the environmental risks associated with the unrestricted use of nanomaterials. The authors compare NMCs with non-therapeutic nanomaterials (NNC) in terms of loading capacity, toxicity, and safety. NMCs exhibit superior loading capacity and lower toxicity compared to NNCs, making them more effective and safer for use. The article also reviews the current strategies for preparing NMCs, including interactions between small molecules, host-guest compounds, and low molecular weight polymers. Challenges and future prospects for the development of NMCs are discussed, emphasizing the need for further research on their industrialization and practical production. The authors conclude that NMCs have the potential to revolutionize nanopesticide technology, offering a promising solution to the current limitations and challenges in agricultural pest control.The article discusses the development and potential of nanopesticides with minimizing carriers (NMC) as a sustainable and environmentally friendly alternative to traditional nanopesticides. NMCs are prepared through prodrug molecular design and molecular self-assembly, aiming to reduce the environmental risks associated with the unrestricted use of nanomaterials. The authors compare NMCs with non-therapeutic nanomaterials (NNC) in terms of loading capacity, toxicity, and safety. NMCs exhibit superior loading capacity and lower toxicity compared to NNCs, making them more effective and safer for use. The article also reviews the current strategies for preparing NMCs, including interactions between small molecules, host-guest compounds, and low molecular weight polymers. Challenges and future prospects for the development of NMCs are discussed, emphasizing the need for further research on their industrialization and practical production. The authors conclude that NMCs have the potential to revolutionize nanopesticide technology, offering a promising solution to the current limitations and challenges in agricultural pest control.