The paper introduces a method to prioritize species for conservation based on both evolutionary distinctiveness (ED) and extinction risk. ED measures a species' contribution to phylogenetic diversity, reflecting its unique evolutionary history. The method accounts for missing species, incomplete phylogenies, and uncertain node ages, making it applicable to poorly known groups. ED scores are robust to taxonomic changes and are comparable across different clades with more than 100 species. The approach is applied to a nearly complete phylogeny of mammals to generate a global priority list, incorporating both phylogenetic diversity and extinction risk. The top 100 species represent a high proportion of mammalian diversity and include many species not typically recognized as conservation priorities. Many evolutionarily distinct and globally endangered species (EDGE species) are not adequately protected by current conservation efforts. The results suggest that existing conservation priorities may need revision to prevent the loss of significant mammalian evolutionary history. The method is applied to a mammalian phylogeny to generate a list of species that are both evolutionarily distinct and globally endangered. ED scores are calculated by dividing the total phylogenetic diversity of a clade among its members. The method is robust to taxonomic changes and is applicable to large phylogenies. The study highlights the importance of considering evolutionary history in conservation planning and suggests that current conservation strategies may not adequately protect evolutionarily distinct species. The paper also discusses the limitations of the method, including the need for accurate phylogenetic data and the potential impact of taxonomic changes on conservation priorities. The study emphasizes the need for a more comprehensive approach to conservation that considers both evolutionary distinctiveness and extinction risk.The paper introduces a method to prioritize species for conservation based on both evolutionary distinctiveness (ED) and extinction risk. ED measures a species' contribution to phylogenetic diversity, reflecting its unique evolutionary history. The method accounts for missing species, incomplete phylogenies, and uncertain node ages, making it applicable to poorly known groups. ED scores are robust to taxonomic changes and are comparable across different clades with more than 100 species. The approach is applied to a nearly complete phylogeny of mammals to generate a global priority list, incorporating both phylogenetic diversity and extinction risk. The top 100 species represent a high proportion of mammalian diversity and include many species not typically recognized as conservation priorities. Many evolutionarily distinct and globally endangered species (EDGE species) are not adequately protected by current conservation efforts. The results suggest that existing conservation priorities may need revision to prevent the loss of significant mammalian evolutionary history. The method is applied to a mammalian phylogeny to generate a list of species that are both evolutionarily distinct and globally endangered. ED scores are calculated by dividing the total phylogenetic diversity of a clade among its members. The method is robust to taxonomic changes and is applicable to large phylogenies. The study highlights the importance of considering evolutionary history in conservation planning and suggests that current conservation strategies may not adequately protect evolutionarily distinct species. The paper also discusses the limitations of the method, including the need for accurate phylogenetic data and the potential impact of taxonomic changes on conservation priorities. The study emphasizes the need for a more comprehensive approach to conservation that considers both evolutionary distinctiveness and extinction risk.