This study examines the impact of marital status on stage at diagnosis, use of definitive therapy, and cancer-specific mortality among patients with 10 leading causes of cancer-related death in the United States. Using data from the Surveillance, Epidemiology, and End Results (SEER) program, researchers analyzed 1,260,898 patients diagnosed between 2004 and 2008. The results show that married patients were less likely to present with metastatic disease, more likely to receive definitive therapy, and had a lower risk of dying from their cancer compared to unmarried patients. These associations remained significant across all cancers studied. The benefits of marriage were greater for males than females. The study highlights the potential impact of social support on cancer detection, treatment, and survival, suggesting that targeted social support interventions could improve outcomes for unmarried patients.This study examines the impact of marital status on stage at diagnosis, use of definitive therapy, and cancer-specific mortality among patients with 10 leading causes of cancer-related death in the United States. Using data from the Surveillance, Epidemiology, and End Results (SEER) program, researchers analyzed 1,260,898 patients diagnosed between 2004 and 2008. The results show that married patients were less likely to present with metastatic disease, more likely to receive definitive therapy, and had a lower risk of dying from their cancer compared to unmarried patients. These associations remained significant across all cancers studied. The benefits of marriage were greater for males than females. The study highlights the potential impact of social support on cancer detection, treatment, and survival, suggesting that targeted social support interventions could improve outcomes for unmarried patients.