Measures of diagnostic accuracy: basic definitions

Measures of diagnostic accuracy: basic definitions

2008 | Ana-Maria Šimundić
The article by Ana-Maria Šimundić from the Department of Molecular Diagnostics at Sestre milosrdnice University Hospital in Zagreb, Croatia, provides a comprehensive overview of measures of diagnostic accuracy. Diagnostic accuracy refers to the ability of a test to discriminate between a target condition and health. Key measures include sensitivity, specificity, predictive values (positive and negative), likelihood ratios (LR+ and LR-), the area under the ROC curve (AUC), diagnostic odds ratio (DOR), and Youden's index. These measures assess different aspects of diagnostic procedures, such as discriminative property and predictive ability. The article emphasizes that these measures are not fixed indicators and are sensitive to factors like disease prevalence, disease spectrum, and study design. It highlights the importance of the STARD initiative in improving the quality of reporting in diagnostic accuracy studies and suggests that scientific journals should incorporate the STARD statement into their guidelines to enhance the reliability and applicability of research findings.The article by Ana-Maria Šimundić from the Department of Molecular Diagnostics at Sestre milosrdnice University Hospital in Zagreb, Croatia, provides a comprehensive overview of measures of diagnostic accuracy. Diagnostic accuracy refers to the ability of a test to discriminate between a target condition and health. Key measures include sensitivity, specificity, predictive values (positive and negative), likelihood ratios (LR+ and LR-), the area under the ROC curve (AUC), diagnostic odds ratio (DOR), and Youden's index. These measures assess different aspects of diagnostic procedures, such as discriminative property and predictive ability. The article emphasizes that these measures are not fixed indicators and are sensitive to factors like disease prevalence, disease spectrum, and study design. It highlights the importance of the STARD initiative in improving the quality of reporting in diagnostic accuracy studies and suggests that scientific journals should incorporate the STARD statement into their guidelines to enhance the reliability and applicability of research findings.
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Understanding Measures of Diagnostic Accuracy%3A Basic Definitions