This study examines the utilization of mental health (MH) services among parents of children with cancer compared to those without. Using nationwide commercial claims data from the Merative MarketScan database, the researchers identified families of children treated for cancer (aged <21 years) between 2010 and 2018, and compared them with families without a child with cancer. The study found that parents of children with cancer had significantly higher probabilities of MH-related visits, particularly for anxiety and depression, compared to other parents. Adjusted analyses showed that families of children with cancer had a 45.7% relative increase in the probability of anxiety-related visits, a 36.1% relative increase in depression-related visits, and a 31.3% relative increase in any MH-related visits. These differences were more pronounced among mothers than fathers. The study highlights the need for targeted interventions to provide counseling and support to better meet the MH care needs of parents and caregivers of children with cancer.This study examines the utilization of mental health (MH) services among parents of children with cancer compared to those without. Using nationwide commercial claims data from the Merative MarketScan database, the researchers identified families of children treated for cancer (aged <21 years) between 2010 and 2018, and compared them with families without a child with cancer. The study found that parents of children with cancer had significantly higher probabilities of MH-related visits, particularly for anxiety and depression, compared to other parents. Adjusted analyses showed that families of children with cancer had a 45.7% relative increase in the probability of anxiety-related visits, a 36.1% relative increase in depression-related visits, and a 31.3% relative increase in any MH-related visits. These differences were more pronounced among mothers than fathers. The study highlights the need for targeted interventions to provide counseling and support to better meet the MH care needs of parents and caregivers of children with cancer.