Mesenchymal stem cells (MSCs) are being explored for drug delivery across the blood-brain barrier (BBB) due to their ability to cross the BBB and deliver therapeutic agents to the brain. MSCs can carry drugs, nanoparticles, or proteins, and have the potential to target injured or damaged brain tissue. They can be used as carriers for various drugs, including low molecular weight compounds like doxorubicin and proteins like interleukin. MSCs can also be genetically modified to express specific proteins or deliver therapeutic agents. MSCs have been used in clinical trials for various neurological conditions, including glioma, Parkinson's disease, Alzheimer's disease, stroke, traumatic brain injury, and multiple sclerosis. MSCs can be modified to enhance their ability to cross the BBB and deliver drugs to the brain. MSCs can be used as carriers for nanoparticles containing biologically active substances, and have the potential to deliver drugs to the brain across the BBB. MSCs are being studied as a promising approach for drug delivery across the BBB, with potential applications in various neurological conditions. The use of MSCs for drug delivery across the BBB is a promising area of research, with potential for future clinical applications.Mesenchymal stem cells (MSCs) are being explored for drug delivery across the blood-brain barrier (BBB) due to their ability to cross the BBB and deliver therapeutic agents to the brain. MSCs can carry drugs, nanoparticles, or proteins, and have the potential to target injured or damaged brain tissue. They can be used as carriers for various drugs, including low molecular weight compounds like doxorubicin and proteins like interleukin. MSCs can also be genetically modified to express specific proteins or deliver therapeutic agents. MSCs have been used in clinical trials for various neurological conditions, including glioma, Parkinson's disease, Alzheimer's disease, stroke, traumatic brain injury, and multiple sclerosis. MSCs can be modified to enhance their ability to cross the BBB and deliver drugs to the brain. MSCs can be used as carriers for nanoparticles containing biologically active substances, and have the potential to deliver drugs to the brain across the BBB. MSCs are being studied as a promising approach for drug delivery across the BBB, with potential applications in various neurological conditions. The use of MSCs for drug delivery across the BBB is a promising area of research, with potential for future clinical applications.