MicroRNAs in plants

MicroRNAs in plants

2002 | Brenda J. Reinhart,1 Earl G. Weinstein,1 Matthew W. Rhoades,1 Bonnie Bartel,2,3 and David P. Bartel1,3
The article by Reinhart et al. (2002) describes the discovery and characterization of microRNAs (miRNAs) in plants, indicating that miRNAs are not unique to animals but also exist in plants. The authors identified 16 Arabidopsis miRNAs, many of which show differential expression patterns during plant development. These miRNAs are processed by the Dicer-like enzyme CARPEL FACTORY (CAF), which is essential for miRNA accumulation. The presence of miRNAs in plants suggests that they arose early in eukaryotic evolution and have likely played a role in the regulation of gene expression in both plants and animals. The study also highlights the conservation of miRNA sequences between Arabidopsis and rice, suggesting that miRNAs have conserved functions across these species. Additionally, the authors discuss the potential roles of miRNAs in plant development, particularly in the context of CAF mutants, and suggest that miRNAs may regulate gene expression through various mechanisms, including translational repression and epigenetic modifications.The article by Reinhart et al. (2002) describes the discovery and characterization of microRNAs (miRNAs) in plants, indicating that miRNAs are not unique to animals but also exist in plants. The authors identified 16 Arabidopsis miRNAs, many of which show differential expression patterns during plant development. These miRNAs are processed by the Dicer-like enzyme CARPEL FACTORY (CAF), which is essential for miRNA accumulation. The presence of miRNAs in plants suggests that they arose early in eukaryotic evolution and have likely played a role in the regulation of gene expression in both plants and animals. The study also highlights the conservation of miRNA sequences between Arabidopsis and rice, suggesting that miRNAs have conserved functions across these species. Additionally, the authors discuss the potential roles of miRNAs in plant development, particularly in the context of CAF mutants, and suggest that miRNAs may regulate gene expression through various mechanisms, including translational repression and epigenetic modifications.
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[slides and audio] MicroRNAs in plants.