The paper reviews the current status of microalgae use for biodiesel production, including their cultivation, harvesting, and processing. It highlights the advantages of microalgae over other feedstocks, such as higher growth rates, lower land requirements, and the potential for environmental benefits like CO₂ sequestration and wastewater treatment. The review covers the historical evolution of microalgae production systems, the viability of microalgae for biodiesel, and the value chain stages involved in microalgae biodiesel production. Key aspects discussed include site selection, algae cultivation, harvesting, biomass concentration, processing, and biodiesel production. The paper also compares open-culture systems (e.g., ponds) with closed-culture systems (e.g., photo-bioreactors) in terms of their advantages and limitations. Overall, the review emphasizes the potential of microalgae as a sustainable and versatile feedstock for biodiesel and other applications, while acknowledging the challenges and ongoing research needed to optimize their use.The paper reviews the current status of microalgae use for biodiesel production, including their cultivation, harvesting, and processing. It highlights the advantages of microalgae over other feedstocks, such as higher growth rates, lower land requirements, and the potential for environmental benefits like CO₂ sequestration and wastewater treatment. The review covers the historical evolution of microalgae production systems, the viability of microalgae for biodiesel, and the value chain stages involved in microalgae biodiesel production. Key aspects discussed include site selection, algae cultivation, harvesting, biomass concentration, processing, and biodiesel production. The paper also compares open-culture systems (e.g., ponds) with closed-culture systems (e.g., photo-bioreactors) in terms of their advantages and limitations. Overall, the review emphasizes the potential of microalgae as a sustainable and versatile feedstock for biodiesel and other applications, while acknowledging the challenges and ongoing research needed to optimize their use.