The article reviews the industrial applications of microbial cellulases, which have shown significant potential in various sectors including pulp and paper, textile, laundry, biofuel production, food and feed industry, brewing, and agriculture. Cellulases, composed of structurally and functionally discrete domains, are produced by a diverse range of microorganisms, including fungi and bacteria. They are involved in the degradation of cellulose and hemicellulose, and their applications in industrial processes have been extensively studied. In the pulp and paper industry, cellulases improve refining efficiency, enhance paper strength, and facilitate deinking. In the textile industry, they are used for biostoning and biopolishing to improve fabric appearance and performance. For bioethanol production, cellulases enable the enzymatic saccharification of lignocellulosic materials, reducing the cost and environmental impact of biofuel production. In the wine and brewing industry, they enhance the quality and yield of fermented products by improving color extraction and filtration. In food processing, cellulases improve the extraction, clarification, and stabilization of fruit and vegetable juices. In animal feed, they enhance the nutritional value and performance of animals by improving the digestibility of feed materials. In agriculture, they aid in crop growth and disease control by degrading plant pathogens. Additionally, cellulases are used in olive oil extraction, carotenoid extraction, and detergent formulations to improve product quality and performance. The article concludes by highlighting the ongoing research and technological advancements in cellulase production and application, emphasizing the importance of protein engineering and enzyme recycling to enhance the economic viability and sustainability of these processes.The article reviews the industrial applications of microbial cellulases, which have shown significant potential in various sectors including pulp and paper, textile, laundry, biofuel production, food and feed industry, brewing, and agriculture. Cellulases, composed of structurally and functionally discrete domains, are produced by a diverse range of microorganisms, including fungi and bacteria. They are involved in the degradation of cellulose and hemicellulose, and their applications in industrial processes have been extensively studied. In the pulp and paper industry, cellulases improve refining efficiency, enhance paper strength, and facilitate deinking. In the textile industry, they are used for biostoning and biopolishing to improve fabric appearance and performance. For bioethanol production, cellulases enable the enzymatic saccharification of lignocellulosic materials, reducing the cost and environmental impact of biofuel production. In the wine and brewing industry, they enhance the quality and yield of fermented products by improving color extraction and filtration. In food processing, cellulases improve the extraction, clarification, and stabilization of fruit and vegetable juices. In animal feed, they enhance the nutritional value and performance of animals by improving the digestibility of feed materials. In agriculture, they aid in crop growth and disease control by degrading plant pathogens. Additionally, cellulases are used in olive oil extraction, carotenoid extraction, and detergent formulations to improve product quality and performance. The article concludes by highlighting the ongoing research and technological advancements in cellulase production and application, emphasizing the importance of protein engineering and enzyme recycling to enhance the economic viability and sustainability of these processes.