The article "Microplastics Exposure: Implications for Human Fertility, Pregnancy, and Child Health" reviews the impact of microplastics (MPs) and nanoplastics (NPs) on human health, particularly focusing on fertility, pregnancy, and child development. MPs and NPs are ubiquitous in the environment, found in oceans, rivers, air, and various biological samples, including human blood, urine, and tissues. These particles can cross physiological barriers and accumulate in organs, causing oxidative stress, inflammation, and disruption of hormonal functions. In males, MPs have been shown to accumulate in the testes, leading to reduced sperm quantity and quality, and altered reproductive hormone levels. In females, MPs and NPs can accumulate in the uterus and ovaries, causing ovarian dysfunction, reduced fertility, and altered estrous cycles. Studies in rodents and humans have demonstrated that exposure to MPs during pregnancy can lead to fetal growth restriction, reduced birth weight, and developmental issues in offspring, including neurological and metabolic disorders. The article highlights the need for further research to understand the long-term effects of MPs on human health, particularly in offspring, and to develop strategies to mitigate exposure risks. It also emphasizes the importance of characterizing different types of MPs and their chemical additives to better assess their toxicity. The authors call for improved methods to measure MPs in various matrices and for more comprehensive studies on the reproductive and developmental impacts of MPs.The article "Microplastics Exposure: Implications for Human Fertility, Pregnancy, and Child Health" reviews the impact of microplastics (MPs) and nanoplastics (NPs) on human health, particularly focusing on fertility, pregnancy, and child development. MPs and NPs are ubiquitous in the environment, found in oceans, rivers, air, and various biological samples, including human blood, urine, and tissues. These particles can cross physiological barriers and accumulate in organs, causing oxidative stress, inflammation, and disruption of hormonal functions. In males, MPs have been shown to accumulate in the testes, leading to reduced sperm quantity and quality, and altered reproductive hormone levels. In females, MPs and NPs can accumulate in the uterus and ovaries, causing ovarian dysfunction, reduced fertility, and altered estrous cycles. Studies in rodents and humans have demonstrated that exposure to MPs during pregnancy can lead to fetal growth restriction, reduced birth weight, and developmental issues in offspring, including neurological and metabolic disorders. The article highlights the need for further research to understand the long-term effects of MPs on human health, particularly in offspring, and to develop strategies to mitigate exposure risks. It also emphasizes the importance of characterizing different types of MPs and their chemical additives to better assess their toxicity. The authors call for improved methods to measure MPs in various matrices and for more comprehensive studies on the reproductive and developmental impacts of MPs.