The study, published in the New England Journal of Medicine, aimed to determine whether mild systemic hypothermia improves neurological outcomes after cardiac arrest due to ventricular fibrillation. The multicenter, randomized, controlled trial involved 275 patients, with 137 assigned to therapeutic hypothermia (target temperature 32°C to 34°C) and 138 to normothermia. The primary endpoint was a favorable neurological outcome within six months, while secondary endpoints included mortality and complications. Results showed that 55% of patients in the hypothermia group had a favorable neurological outcome compared to 39% in the normothermia group (risk ratio 1.40, 95% CI 1.08 to 1.81). Mortality at six months was 41% in the hypothermia group and 55% in the normothermia group (risk ratio 0.74, 95% CI 0.58 to 0.95). The complication rate did not differ significantly between the groups. The study concluded that mild therapeutic hypothermia increased the rate of favorable neurological outcomes and reduced mortality in patients successfully resuscitated after cardiac arrest due to ventricular fibrillation.The study, published in the New England Journal of Medicine, aimed to determine whether mild systemic hypothermia improves neurological outcomes after cardiac arrest due to ventricular fibrillation. The multicenter, randomized, controlled trial involved 275 patients, with 137 assigned to therapeutic hypothermia (target temperature 32°C to 34°C) and 138 to normothermia. The primary endpoint was a favorable neurological outcome within six months, while secondary endpoints included mortality and complications. Results showed that 55% of patients in the hypothermia group had a favorable neurological outcome compared to 39% in the normothermia group (risk ratio 1.40, 95% CI 1.08 to 1.81). Mortality at six months was 41% in the hypothermia group and 55% in the normothermia group (risk ratio 0.74, 95% CI 0.58 to 0.95). The complication rate did not differ significantly between the groups. The study concluded that mild therapeutic hypothermia increased the rate of favorable neurological outcomes and reduced mortality in patients successfully resuscitated after cardiac arrest due to ventricular fibrillation.