supplemental data for "mitochondrial fusion protects against neurodegeneration in the cerebellum" include tables and figures. table s1 shows the lethality of meox2-cre/mfnloxp mice, with 5 wild-type and 6 mutant mice tested weekly. each mouse underwent three trials, with average times ± standard deviation. table s2 presents the rotarod test results for l7-cre/mfn2loxp mice. figure s1 shows conditional mfn1 and mfn2 knockouts, including schematic diagrams of targeting constructs, pcr genotyping, and mitochondrial morphology in mfn1loxp mefs. figure s2 depicts degeneration of pcs in meox2-cre/mfn2loxp and wnt1-cre/mfn2loxp mice, showing anti-calbindin if at indicated ages. figure s3 shows electron transport compromise in young l7-cre/mfn2loxp mice, with cox and sdh staining of 6-week-old cerebellas. figure s4 shows ultrastructure of mfn1-deficient pcs, including representative em images of 7-week-old meox2-cre/mfn1loxp cerebellum and 9-week-old l7-cre mice with pcs of genotype mfn1-/-, mfn2+/-, showing normal mitochondrial morphology and distribution. scale bars indicate 0.5 μm.supplemental data for "mitochondrial fusion protects against neurodegeneration in the cerebellum" include tables and figures. table s1 shows the lethality of meox2-cre/mfnloxp mice, with 5 wild-type and 6 mutant mice tested weekly. each mouse underwent three trials, with average times ± standard deviation. table s2 presents the rotarod test results for l7-cre/mfn2loxp mice. figure s1 shows conditional mfn1 and mfn2 knockouts, including schematic diagrams of targeting constructs, pcr genotyping, and mitochondrial morphology in mfn1loxp mefs. figure s2 depicts degeneration of pcs in meox2-cre/mfn2loxp and wnt1-cre/mfn2loxp mice, showing anti-calbindin if at indicated ages. figure s3 shows electron transport compromise in young l7-cre/mfn2loxp mice, with cox and sdh staining of 6-week-old cerebellas. figure s4 shows ultrastructure of mfn1-deficient pcs, including representative em images of 7-week-old meox2-cre/mfn1loxp cerebellum and 9-week-old l7-cre mice with pcs of genotype mfn1-/-, mfn2+/-, showing normal mitochondrial morphology and distribution. scale bars indicate 0.5 μm.