15 JUNE 2007 | Thilo Womelsdorf, Jan-Mathijs Schoffelen, Robert Oostenveld, Wolf Singer, Robert Desimone, Andreas K. Engel, Pascal Fries
This article discusses how neuronal interactions are modulated by synchronization of rhythmic activities. It shows that the phase relationship between rhythmic activities in different neuronal groups determines the strength of their mutual influence. The study used data from four different animal models, including cats and monkeys, to analyze the relationship between phase relations and power correlations in neuronal activity. The results indicate that when the phase relations between neuronal groups are synchronized, their mutual influence is stronger. This effect was observed in both MUA-MUA and MUA-LFP pairs, with the strongest effect seen in the gamma-frequency band (30-100 Hz). The study also found that the phase relations between neuronal groups are not random, and that the synchronization of these relations can enhance the effective strength of connections between groups. The findings suggest that synchronization plays a crucial role in neuronal interactions, and that the pattern of synchronization can flexibly determine the pattern of neuronal interactions. The study also highlights the importance of phase relations in cognitive functions, such as visual attention, and suggests that synchronization may be a key mechanism underlying these functions. The results have implications for understanding how the brain processes information and how attention influences neural activity.This article discusses how neuronal interactions are modulated by synchronization of rhythmic activities. It shows that the phase relationship between rhythmic activities in different neuronal groups determines the strength of their mutual influence. The study used data from four different animal models, including cats and monkeys, to analyze the relationship between phase relations and power correlations in neuronal activity. The results indicate that when the phase relations between neuronal groups are synchronized, their mutual influence is stronger. This effect was observed in both MUA-MUA and MUA-LFP pairs, with the strongest effect seen in the gamma-frequency band (30-100 Hz). The study also found that the phase relations between neuronal groups are not random, and that the synchronization of these relations can enhance the effective strength of connections between groups. The findings suggest that synchronization plays a crucial role in neuronal interactions, and that the pattern of synchronization can flexibly determine the pattern of neuronal interactions. The study also highlights the importance of phase relations in cognitive functions, such as visual attention, and suggests that synchronization may be a key mechanism underlying these functions. The results have implications for understanding how the brain processes information and how attention influences neural activity.